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Lifespan cover art

Lifespan

By: Dr David A. Sinclair, Matthew D. LaPlante
Narrated by: Dr David A. Sinclair
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Summary

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help listeners live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease – it is inevitable.

But what if everything you think you know about ageing is wrong?

What if ageing is a disease? And that disease is curable.

In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan – he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick – a circuit designed to halt reproduction in order to repair damage to the genome –has enabled earth’s early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Listeners will discover how a few simple lifestyle changes – like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy – can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like – and what will need to change – when we are all living well to 120 or more.

Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. LIFESPAN is destined to be the biggest book on genes, biology, and longevity of this decade.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2019 Dr David A. Sinclair (P)2019 HarperCollins Publishers Limited

Critic reviews

‘If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant.’ – Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and #1 New York Times bestselling author

‘This is the most visionary book about aging I have ever read. Seize the day–and seize this book!’ – Dean Ornish, MD, founder & president, Preventive Medicine Research Institute, and New York Times bestselling author of UnDo It!

‘In this insightful and provocative book that asks questions about how we age, and whether humans can overcome decay and degeneration, Sinclair grapples with some of the most fundamental questions around the science of aging. The result is an elegant and exciting book that deserves to be read broadly and deeply.’ – Siddhartha Mukherjee, Pulitzer Prize–winning and #1 New York Times bestselling author

What listeners say about Lifespan

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Life never be the same

Must read it, if you want to understand the direction of the future, get practical knowledge on health, be aware of yourself.
Life changing book!

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  • Overall
    5 out of 5 stars

Very interesting, relevant and well explained.

A very interesting, relevant and well explained book, which was well read and I also liked the inverviews between chapters.

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Impressive!

One of the rare books that challenged and changed me. Sinclair works towards changing the world as we know it.

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Grateful

So glad to have listen to this. The informations are so valuable to long life

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    4 out of 5 stars

Interesting information, but also a personal story

The reading is personal, personable and passionate. The interjections by the authors are interesting and add flavour to the book.
There's a ton of interesting information in here and it's very definitely worth reading.
On the one hand it's told as a personal tale and that adds something, on the other hand it becomes personal political and culture biased in a way that's not pleasant (depending which culture is receiving the bashing).
On balance, read the book, if you're interested in the subject, you'll get a lot out of it.

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Listen to this now!

Loved it. One of the most compelling things I've read in years. I've already changed my habits.

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very interesting stuff, will listen again

really enjoyed the book. at points a little to science heavy, I've a simple mind and was somewhat lost at times.

however, overall a really good listen. definitely made me reevaluate my life and choices.

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Respect for the authors work but less ideology please

A lot of respect for Sinclair’s work, I would have liked a more about the science and getting deeper into that end of things. It’s amazing what is possible and this is a good general overview. I would liked less blending in of personal ideologies and blind suport for some influence that the author has by being courted by the rich and the elite, I can’t help but wonder if that does affect some of the soap box moments in the book. Not sure if the so called thought leaders mentioned are not as much part of the problem as they profess to be part of the solution, as Sinclair goes there a lot has to be part of any assessment of this book. However much respect for the author as a scientist, much respect for his.

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  • 28-01-23

Very informative

This book provides a very profound set of ideas, it has helped me to understand the process of aging and what I can do to slow or reverse the process. It covers the social and economic aspects of this medical development and puts forward an optimistic future for humanity.

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good stuff

very good health info regarding longevity and health, not so good on climate change and vaccine science, very mainstream and false narratives.

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