Showing titles in Genetics

Being human entails an astonishingly complex interplay of biology and culture, and while there are important differences between women and men, there is a lot more variation and overlap than we may realize. Sex Is a Spectrum offers a bold new paradigm for understanding the biology of sex, drawing on the latest science to explain why the binary view of the sexes is fundamentally flawed.

What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.

For the past six years, Whitney Dafoe has been confined to a bedroom in the back of his parents' home, unable to walk, eat or speak. His diagnosis? The mysterious disease myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) which affects 20 million people around the world who largely...

First there was the genetic revolution—the discovery that physical structures in the cell, including DNA and RNA, shape every organism. Now, says evolutionary biologist Richard Sternberg, we are overdue for another and more profound revolution. Recent findings reveal that genetic and even epigenetic sources alone cannot account for the rich dynamism of life—not even close. Some other informational source is required.

A revelatory account of how power, politics, and greed have placed the unfulfilled promise of personalized medicine at the center of American medicine The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our...

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.

¿De dónde venimos? ¿Quiénes somos? ¿Adónde vamos? A estas preguntas atemporales responde el reconocido genetista Lluís Quintana-Murci, mostrando cómo el incremento del conocimiento obtenido en las pasadas décadas por la genética de poblaciones ha transformado nuestro conocimiento de la especie.

Race has provided the rationale and excuse for some of the worst atrocities in human history. Yet, according to many biologists, physical anthropologists, and geneticists, there is no valid scientific justification for the concept of race. To be more precise, although there is clearly some physical basis for the variations that underlie perceptions of race, clear boundaries among "races" remain highly elusive from a purely biological standpoint.

Most people know that Gregor Mendel, the Moravian monk who patiently grew his peas in a monastery garden, shaped our understanding of inheritance. But people might not know that Mendel's work was ignored in his own lifetime, even though it contained answers to the most pressing questions raised by Charles Darwin's revolutionary book, On Origrin of the Species, published only a few years earlier. Mendel's single chance of recognition failed utterly, and he died a lonely and disappointed man.

“Constantly fascinating and impeccably reported...You won’t look at yourself in the same way again.” —Ed Yong, bestselling author of An Immense World and I Contain Multitudes A captivating exploration of the remarkable ways our DNA mutates over the course of our lives, with radical...

With genetics and genetic engineering receiving almost daily coverage in the media, this audiobook is an introduction for general listeners who wish to know more about a science that is changing our world. Starting with the history of genetics, from primitive breeding programmes to Mendel's Law, and moving on to a full explanation of genetics and its role in our future, this is a comprehensive survey of genetics past, present and future.

Inevitably, life on Earth will come to an end, whether by climate disaster, cataclysmic war, or the death of the sun in a few billion years. To avoid extinction, we will have to find a new home planet, perhaps even a new solar system, to inhabit. In this provocative and fascinating book, Christopher Mason argues that we have a moral duty to do just that.

Our understanding of bacterial genetics has progressed as the genomics field has advanced. Genetics and genomics complement and influence each other; they are inseparable. Under the novel insights from genetics and genomics, once-believed borders in biology start to fade: biological knowledge of...

Po Bronson and Arvind Gupta, venture capitalists from Silicon Valley, take everyday news headlines and decode them, leading us on a journey through their unique and highly entertaining view of the world. Each chapter is prefaced with a real-world headline from today's chaotic news cycle: dying bees. Rogue planets. Beyond Meat. Glaciers melting. Bronson and Gupta decipher what's really going on behind these headlines, and why. 

This book raises ethical questions that might become part of mainstream consciousness in years to come and points out the role of communication and language in helping create (or avoid) a potentially dystopian future.

Psychiatric Pharmacogenetics is a book written by a physician and scientist - both renowned in the field of psychiatric pharmacogenetics - and written specifically for the busy practitioner. It gives a synopsis of the history of how the science of pharmacogenetics evolved, and gives a basic but detailed overview of the science which is rooted in the Cytochrome P450 system.

Delve deeper into the scientific terms and theories at the core of the Peabody-winning, cult favorite show. With exclusive insights from the show's cocreator, Graeme Manson, and science consultant Cosima Herter, The Science of Orphan Black takes you behind the closed doors of the Dyad Institute and inside Neolution.

Bloomsbury presents Proto by Laura Spinney, read by Emma Spurgin-Hussey The enthralling story of how today’s largest language family, spoken by nearly half the world’s population, descended from one ancient dialect. Daughter. Duhitár-. Dustr. Dukte. Listen to these English, Sanskrit...

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

In this book, the author provides a real-life example of the shocking revelations and aftermath of DNA investigation. Growing up as one of nine children, Stephen Anderson suspected from a young age that something was amiss. A chance accident, and a small crack in the history of his family broke open. More would come to be revealed as the author sets out on a journey to find answers to his questions. Any listener wondering what a DNA test might reveal will find here one extreme example of family secrets gone awry.

A completely new way to look at fat loss, autoimmune conditions, and optimal health. What if that banana you had for breakfast was actually sabotaging your health efforts? Health, metabolism, and weight are controlled by both our genetics and our lifestyle, in essence a balance between nature and nurture. By identifying our strengths and our weaknesses genetically, as well as our body chemistry through advanced targeted testing, we now have the ability to influence our health like never before.

The field of biotechnology has evolved over the past four decades, developing medicines which are curing diseases. But this journey of success has been tough and arduous, built upon the shoulders of major failures. Good Genes Gone Bad highlights seven such colossal failures in drug...

Une extraordinaire histoire collective dont nous sommes tous les héritiers ! Les gènes sont une fascinante machine à remonter le temps depuis que nous savons faire "parler" non seulement l'ADN des Sapiens actuels, mais aussi celui de nos lointains ancêtres. Évelyne Heyer, biologiste française, professeure en génétique des populations, dévoile un récit de l'aventure humaine dans un style clair et accessible.

A practical, helpful guide on how to fight back against Alzheimer’s disease—with expert medical advice and one woman’s inspiring personal journey. Jamie Tyrone was forty-nine years old when she learned by accident through genetic testing that she had a 91% chance of getting Alzheimer's...

New York Times bestselling author and former FDA Commissioner Scott Gottlieb provides a glimpse of a promising future that is quickly approaching: a world with cures for chronic illnesses and cancers. While traditional drugs mostly help us manage the effects of disease, cell therapies promise...

From the author of Seed of Israel: DNA Guide to Tracing Your Jewish Ancestry comes this great dive into the history of Ashkenazi Jews. While controversial debates spark disagreements on the crystallization of this Jewish Diaspora, modern genetic studies and personal DNA samples finally conclude the Levantine Middle Eastern and Mediterranean roots of Ashkenazi ancestry: Judean people from the Holy Land that journeyed across the Mediterranean to the bottleneck of Europe.

In the aftermath of an asteroid impact, Earth’s power grid is damaged nearly beyond recovery. The survival of our world may well depend on energy sources collected from an abandoned undersea settlement beneath the icy surface of Enceladus. Earth-raised Colonel Carter Rhodes, in charge of Earth’s recovery efforts, calls upon Gwen Baré, a Venusian engineer, to regain control of the deserted moon outpost and collect fuel for Earth’s collapsing power grids.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Die CRISPR-Methode und die Zukunft der Medizin. Was macht die Natur, wenn ein neuer Feind auftaucht? Sie findet eine neue Strategie. Wenn eine Bakterie von einem Virus attackiert wird, verteidigt sie sich beispielsweise, indem sie ihre genetische Struktur ändert. Doch wie können diese Mechanismen nachgewiesen werden? Und welchen Nutzen hat dieses Wissen für die Medizin? Der Amerikanerin Jennifer Doudna und der Französin Emmanuelle Charpentier sind bahnbrechende Erkenntnisse im Bereich der Biochemie gelungen.

Since the birth of civilization, human beings have manipulated other life-forms. We have selectively bred plants and animals for thousands of years to maximize agricultural production and cater to our tastes in pets. The observation of the creation of artificial animal and plant variants was a key stimulant for Charles Darwin's theory of evolution. The ability to directly engineer the genomes of organisms first became possible in the 1970s, when the gene for human insulin was introduced into bacteria.

A Genetic Portrait of America In this fascinating exploration, geneticist Bryan Sykes turns his sights on the United States, one of the most genetically variegated countries in the world. From the blue-blooded pockets of old-WASP New England to the vast tribal lands of the Navajo, Bryan Sykes...

Already technology enables parents to select some genetic traits for their children, and soon it will be possible to begin to shape ourselves as a species. Countering loud cries of alarm, bioethics expert Ronald Green explains why our fears about genetic engineering are overblown and how we can move forward responsibly to create a better future.

"A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." —Siddhartha Mukherjee MD, New York Times bestselling author of The Emperor of All Maladies and The Gene A groundbreaking exploration of genetic...

Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA - but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain - and what might we give up in return? 

Since 2010 it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease." As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

Brian and Deborah Charlesworth provide a clear and concise summary of the process of evolution by natural selection, and how natural selection gives rise to adaptations and eventually, over many generations, to new species. They introduce the central concepts of the field of evolutionary biology, as they have developed since Darwin and Wallace on the subject, over 140 years ago, and discuss some of the remaining questions regarding processes.