Showing titles in Genetics

In From Darwin to Derrida, evolutionary biologist David Haig explains how a physical world of matter in motion gave rise to a living world of purpose and meaning. Natural selection, a process without purpose, gives rise to purposeful beings who find meaning in the world. The key to this, Haig proposes, is the origin of mutable “texts”―genes―that preserve a record of what has worked in the world. These texts become the specifications for the intricate mechanisms of living beings.

For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo--Evolutionary Developmental Biology--is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

Audio Bonus! Includes exclusive conversations with the authors! A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly...

How could a relatively simple chemical code give rise to the complexity of a human being? How could our human genome have evolved? And how does it actually work? Your genome defines you at the most profound level. That same genome is present in every one of the approximately 100,000 billion cells that make you who you are as an individual member of the human species. An important ingredient of the genome, and its essential nature, is memory .

Today, with relatively easy access to our DNA ancestry, we have more data about ourselves and family history than previous generations could have imagined. In the 12 fascinating lessons of Identity in the Age of Ancestral DNA, Anita Foeman, PhD, professor of communication and media, and founder and primary investigator of the DNA Discussion Project at West Chester University, takes us behind the scenes to examine what really happens when individuals receive their personal DNA ancestry results.

Cancer has always been with us. It killed our hominid ancestors, the mammals they evolved from and the dinosaurs that trampled the ground before that. Tumours grow in pets, livestock and wild animals. Even tiny jelly-like Hydra - creatures that are little more than a tube full of water - can get cancer. Paradoxically, many of us think of cancer as a contemporary killer, a disease of our own making caused by our modern lifestyles. 

In The Genealogical Adam and Eve, S. Joshua Swamidass tests a scientific hypothesis: What if the traditional account is somehow true, with the origins of Adam and Eve taking place alongside evolution? Building on well-established but overlooked science, Swamidass explains how it's possible for Adam and Eve to be rightly identified as the ancestors of everyone. 

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

 DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction. 

Are humans unwitting partners in evolution with psychedelic plants? Darwin’s Pharmacy shows they are by weaving the evolutionary theory of sexual selection and the study of rhetoric together with the science and literature of psychedelic drugs. Long suppressed as components of the human tool kit, psychedelic plants can be usefully modeled as “eloquence adjuncts” that intensify a crucial component of sexual selection in humans: discourse.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

For the past six years, Whitney Dafoe has been confined to a bedroom in the back of his parents' home, unable to walk, eat or speak. His diagnosis? The mysterious disease myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) which affects 20 million people around the world who largely suffer in silence because the condition is little known and much misunderstood. Waiting for Superman follows Whitney's father, groundbreaking geneticist Ron, as he uncovers new possibilities for treatments and potentially a cure. 

Bloomsbury presents Proto by Laura Spinney, read by Emma Spurgin-Hussey The enthralling story of how today’s largest language family, spoken by nearly half the world’s population, descended from one ancient dialect. Daughter. Duhitár-. Dustr. Dukte. Listen to these English, Sanskrit...

An award-winning physician and scientist makes the game-changing case that genetic females are stronger than males at every stage of life 'A powerful antidote to the myth of a "weaker sex"' Gina Rippon, author of The Gendered Brain From birth, genetic females are better at fighting viruses...

The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?

A revelatory account of how power, politics, and greed have placed the unfulfilled promise of personalized medicine at the center of American medicine The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our...

A look at the extraordinary ways the brain turns thoughts into actions - and how this shapes our everyday lives. In On Task, cognitive neuroscientist David Badre presents the first authoritative introduction to the neuroscience of cognitive control - the remarkable ways that our brains devise sophisticated actions to achieve our goals. We barely notice this routine part of our lives. Yet, cognitive control, also known as executive function, is an astonishing phenomenon that has a profound impact on our well-being.   

When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments.

Синтетическая биология преобразит наше понимание семейных связей, время нашего старения, то, чем мы лечимся, где живем и что едим. В этой бурно развивающейся области, задействующей компьютеры для исправления и изменения генетического кода, уже разработаны революционные решения—от мРНК-вакцин и диагностики врожденных заболеваний у эмбрионов до выращенного в лаборатории мяса, которое на вкус почти неотличимо от настоящего. Она дает нам шанс справиться с глобальными угрозами—изменением климата, нехваткой еды и энергетическим кризисом.

A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation, but also experience related conditions themselves.