Gavin Sasaki was a promising young journalist in New York City until the day he was fired for plagiarism. The last thing he wants is to sell foreclosed real estate for his sister Eilo's company in their Florida hometown, but he's in no position to refuse her job offer. Plus, there's another reason to go home: Eilo recently met a 10-year-old girl who looks very much like Gavin and has the same last name as his high-school girlfriend, Anna, who left town abruptly after graduation.

When Lilia Albert was a child, her father appeared on the doorstep of her mother's house and took her away. Now, haunted by an inability to remember much about her early childhood, Lilia moves restlessly from city to city, abandoning lovers and eluding the private detective who has dedicated a career to following close behind. Then comes Eli.

Amanda and Clay head to a remote corner of Long Island expecting a holiday: a quiet reprieve from life in New York City, quality time with their teenage son and daughter and a taste of the good life in the luxurious home they've rented for the week. But with a late-night knock on the door, the spell is broken. Ruth and G. H., an older couple who claim to own the home, have arrived there in a panic. These strangers say that a sudden power outage has swept the city, and - with nowhere else to turn - they have come to the country in search of shelter. 

Day one: The Georgia Flu explodes over the surface of the Earth like a neutron bomb. News reports put the mortality rate at over 99%. Week Two: Civilization has crumbled. Year Twenty: A band of actors and musicians called the Travelling Symphony move through their territories performing concerts and Shakespeare to the settlements that have grown up there. Twenty years after the pandemic, life feels relatively safe. But now a new danger looms, and it threatens the hopeful world every survivor has tried to rebuild.

Stories tucked away on every floor. No. 10 Luckenbooth Close is an archetypal Edinburgh tenement. The devil’s daughter rows to the shores of Leith in a coffin. The year is 1910, and she has been sent to a tenement building in Edinburgh by her recently deceased father to bear a child for a wealthy man and his fiancée. The harrowing events that follow lead to a curse on the building and its residents - a curse that will last for the rest of the century.

Lizzie Benson slid into her job as a librarian without a traditional degree. But this gives her a vantage point from which to practise her other calling: as an unofficial shrink. For years, she has supported her God-haunted mother and her recovering addict brother. They have both stabilized for the moment, but then her old mentor, Sylvia Liller, makes a proposal. Sylvia has become famous for her prescient podcast, 'Hell and High Water', and wants to hire Lizzie to answer the mail she receives: from left-wingers worried about climate change and right wingers worried about the decline of western civilization.

Mickey Fitzpatrick has been patrolling the 24th District for years. She knows most of the working women by name. She knows what desperation looks like and what people will do when they need a fix. She’s become used to finding overdose victims: their numbers are growing every year. But every time she sees someone sprawled out, slumped over, cold to the touch, she has to pray it’s not her sister, Kacey. 

On the longest day of the summer, 12 people sit cooped up with their families in a faded Scottish cabin park. The endless rain leaves them with little to do but watch the other residents. A woman goes running up the Ben as if fleeing; a retired couple reminisces about neighbours long since moved on; a teenage boy braves the dark waters of the loch in his red kayak. Each person is wrapped in their own cares but increasingly alert to the makeshift community around them. 

Bea's five-year-old daughter, Agnes, is slowly wasting away. The smog and pollution of the overdeveloped, overpopulated metropolis they call home is ravaging her lungs. Bea knows she cannot stay in the City, but there is only one alternative: the Wilderness State. Mankind has never been allowed to venture into this vast expanse of untamed land. Until now. Bea and Agnes join 18 other volunteers who agree to take part in a radical experiment. 

Cal Hooper thought a fixer-upper in a remote Irish village would be the perfect escape. After 25 years in the Chicago police force and a bruising divorce, he just wants to build a new life in a pretty spot with a good pub where nothing much happens. But then a local kid comes looking for his help. His brother has gone missing and no one, least of all the police, seems to care. Cal wants nothing to do with any kind of investigation, but somehow he can't make himself walk away.

The year is 1969. In a housing project in south Brooklyn, a shambling old church deacon called Sportscoat shoots - for no apparent reason - the local drug-dealer who used to be part of the church's baseball team. The repercussions of that moment draw in the whole community, from Sportscoat's best friend - Hot Sausage - to the local Italian mobsters, the police (corrupt and otherwise), and the stalwart ladies of the Five Ends Baptist Church.

On a summer's day in 1596, a young girl in Stratford-upon-Avon takes to her bed with a fever. Her twin brother, Hamnet, searches everywhere for help. Why is nobody at home? Their mother, Agnes, is over a mile away, in the garden where she grows medicinal herbs. Their father is working in London. Neither parent knows that one of the children will not survive the week.

Casey has ended up back in Massachusetts after a devastating love affair. Her one constant is the novel she has been writing for six years, but at 31 she is in debt and directionless, and feels too old to be that way - it’s strange, not be the youngest kind of adult anymore. Suddenly Casey finds herself at the point of a love triangle, torn between two very different relationships that promise two very different futures.

Vanessa Wye was 15 years old when she first had sex with her English teacher. She is now 32 and the teacher, Jacob Strane, has just been accused of sexual abuse by another former student of his. Vanessa is horrified by this news, because she is quite certain that the relationship she had with Strane wasn’t abuse. It was love. She’s sure of that. But now, in 2017, in the midst of allegations against powerful men, she is being asked to redefine the great love story of her life - her great sexual awakening - as rape.  

When glamorous socialite Noemí Taboada receives a frantic letter from her newlywed cousin begging to be rescued from a mysterious doom, it's clear something is desperately amiss. Catalina has always had a flair for the dramatic, but her claims that her husband is poisoning her and her visions of restless ghosts seem remarkable, even for her. Noemí's chic gowns and perfect lipstick are more suited to cocktail parties than amateur sleuthing, but she immediately heads to High Place, a remote mansion in the Mexican countryside, determined to discover what is so affecting her cousin.