RECOVER-TLC released a public update on four major long COVID treatment trials. Many patients are asking the same question: how close are we to an approved treatment?

In this episode, I break down how RECOVER-TLC chooses treatments to study, why the research process takes so long, and where each of the four current trials stands right now. I’ll also explain what this progress realistically means for people living with long COVID—without hype and without false hope.

This video is for people who want a clear, honest explanation of long COVID research and timelines, and who want to understand how close—or far—we really are from approved treatments.

In this episode:
-Why approved long COVID treatments take so long
-How RECOVER-TLC selects and designs clinical trials
-Updates on baricitinib, low-dose naltrexone, GLP-1 agonists, and stellate ganglion block
-What this research means for patients right now

Chapters:
00:00 Understanding Long COVID and Research Delays
01:43 The Process of Choosing Targets
03:49 Designing Clinical Trials
07:32 Join the Community
08:25 Baricitinib
09:54 Low Dose Naltrexone (LDN)
11:08 Semaglutide: Exploring GLP-1 Treatments
14:08 Stellate Ganglion Block
16:52 Key Takeaways and Future Outlook

#longCOVID #COVID #fatigue #MECFS #POTS #medicine #science #RECOVERTLC #NIH #FDA #NIAID

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Many people with long COVID see early improvement—then hit a recovery plateau. In this episode, physician and long COVID patient Dr. Zeest Khan explains why long COVID recovery stalls and the three patterns she sees most often when progress gets stuck.

Topics covered:

• Why long COVID recovery plateaus
• The push-crash cycle and energy envelope
• Mental health, grief, and decision-making in chronic illness
• Why trying treatments at random can backfire
• How to think strategically instead of reactively

Episodes referenced:

#43: Sensory Integration Therapy for Long COVID

Support the show

Subscribe for free written summaries of each episode, resources, and more. LongCovidMD.substack.com/subscribe

Support by donating at BuyMeACoffee

For immediate crisis support in the U.S., call or text 988 to reach the Suicide & Crisis Lifeline, offering free, confidential 24/7 help for mental health, substance use, or emotional distress via call, text, or chat.

Support the show

Subscribe for free written summaries of each episode, resources, and more. LongCovidMD.substack.com/subscribe

Support by donating at BuyMeACoffee