In this episode of Skin Anarchy, Dr. Ekta Yadav sits down with Dr. Tiffany Libby for a clear, science-forward conversation on supplements, cellular energy, and why NAD biology has become such a focal point in modern longevity discussions. As interest in “aging better” grows, this episode cuts through hype to explore what NAD optimization can—and cannot—realistically do for skin and whole-body health.

Dr. Libby brings a rare perspective to the conversation. As a board-certified dermatologist and Director of Mohs Surgery at Brown University Health, her work spans both skin cancer care and cosmetic dermatology, treating patients across decades of life. That long view has shaped her understanding of longevity not as youth preservation, but as maintaining resilience, repair capacity, and function over time—especially in the face of inflammation, environmental stress, and chronic disease.

Much of the discussion centers on why supplements, particularly NAD boosters, are having a cultural moment. Dr. Libby explains that this surge reflects a gap in the healthcare system itself—one that prioritizes treatment over prevention. While supplements can offer support, she emphasizes they are not shortcuts. Longevity still rests on fundamentals: sleep, nutrition, movement, stress regulation, and inflammation control.

The episode offers a practical breakdown of NAD (nicotinamide adenine dinucleotide), explaining its role in mitochondrial energy production, DNA repair, and cellular defense. As NAD levels decline with age, skin becomes less efficient at repairing damage, producing collagen, and maintaining barrier integrity. Crucially, Dr. Libby explains why NAD itself can’t be absorbed directly—and why precursors like nicotinamide riboside (NR) matter instead.

Throughout the conversation, skepticism and safety remain central themes. In an underregulated supplement space, quality, dosing, and clinical validation matter. From a dermatologic standpoint, supporting mitochondrial health may help skin function closer to its biological potential—but only when paired with evidence-based care and realistic expectations.

Listen to the full episode of Skin Anarchy to hear Dr. Tiffany Libby unpack the science of NAD, cellular energy, and why longevity begins with supporting biology—not chasing promises.

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In this episode of Skin Anarchy, Dr. Ekta Yadav welcomes Carolina Reis Oliveira and Alessandra Zonari, co-founders of OneSkin, for a rigorous, eye-opening conversation that reframes skincare as a true longevity intervention. Part of the Lessons in Longevity series, this episode asks a bold question: what if skin aging isn’t cosmetic at all—but cellular, systemic, and deeply biological?

OneSkin began not as a brand, but as a lab-based mission. Trained in stem cell biology, tissue engineering, and genomics, Carolina and Alessandra spent years growing real human skin in the lab to test existing products. What they found challenged the industry: many so-called “anti-aging” formulas increased inflammation, cellular stress, and long-term damage. Meanwhile, longevity science was accelerating—yet skin, the body’s largest organ, was being left out of the conversation.

At the center of the episode is cellular senescence—a state where damaged cells stop dividing and begin secreting inflammatory signals that degrade surrounding tissue. In skin, this process weakens the barrier, disrupts collagen, and accelerates visible aging. Rather than masking symptoms, OneSkin set out to target this root cause. After screening hundreds of compounds, they developed OS-01, a proprietary peptide shown in lab models to significantly reduce senescent cell burden while increasing collagen—without irritation.

The conversation also expands beyond the face. OneSkin’s decision to focus on body skin revealed something unexpected: improving the skin barrier may reduce systemic inflammation. Clinical data discussed in the episode suggests that healthier skin doesn’t just look better—it may influence whole-body aging.

This episode is a must-listen for anyone curious about where skincare, biotech, and longevity science truly intersect.

Listen to the full episode of Skin Anarchy to hear how OneSkin is redefining skin as a living organ—and why the future of longevity may start at the surface.

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In this Fragrance Friday episode of Skin Anarchy, Dr. Ekta sits down with Pissara Umavijani, founder and perfumer of Parfums Dusita, for a quietly powerful conversation about perfume as emotion, memory, and meaning. In an industry increasingly driven by trends and virality, Dusita stands apart as a house built on poetry, patience, and feeling.

Pissara shares her deeply personal journey—leaving Thailand to start over in Paris with a singular intention: to create fragrance that makes people feel. Entirely self-taught, she immersed herself in the craft of perfumery through persistence and intuition, guided by a belief that scent should communicate something human, not perform for attention. Even the name Dusita, which refers to a level of paradise in Thai culture, reflects this ethos—living with purpose, warmth, and emotional presence.

Rather than relying on obvious cultural motifs, Dusita expresses Thai heritage through values: gentleness, hospitality, compassion, and balance. These qualities shape not only the fragrances themselves, but how the brand engages with people—inviting closeness rather than spectacle.

At the heart of every Dusita fragrance is poetry written by Pissara’s late father. Each poem serves as an emotional blueprint, translated into scent rather than illustrated literally. This approach comes to life in beloved creations like Tonka Latte, a soft, comforting gourmand inspired by warmth and love, and Pavilion d’Or, a serene composition that captures balance and stillness without adhering to a single category.

Throughout the conversation, Pissara returns to one guiding principle: balance. For her, great perfumery isn’t about intensity—it’s about harmony, evolution, and restraint. Dusita’s fragrances don’t demand attention; they reward it.

Listen to the full Skin Anarchy episode to hear how poetry, Thai cultural values, and emotional honesty shape Parfums Dusita—and why the most powerful fragrances are often the quietest ones.

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