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🎙️Join us as we finish our discussion through Kidney Cancer with the wonderful Professor Daniel Heng of Calgary,Canada🇨🇦

🎙️In this episode we focus on the Real World Evidence 🌎🔎 from the IMDC

🎙️what cane we learn from comparing complete response rates and durable responses between IO-IO therapy and IO-VEGF therapy🤔

🎙️What has Danny learned through setting up the IMDC and how to bring people with you?

🎙️What areas does Danny think need expanding in the future in Renal Cancer?

All this and more alongside some genuine laughter 😂with Danny

Enjoy!!!

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🚨Join us today as we discuss all things kidney cancer !!

💥We are Hanging with the Heng! The legend that is Professor Daniel Heng (AKA DannyHeng tm) from The Albert Child Cancer Centre, Calgary, Canada🇨🇦

🎙️We hear how Danny Heng started the IMDC (International Metastatic renal cell carcinoma Database Consortium) prognostic score in advanced kidney cancer.

🎙️We discuss how the IMDC moved as prognostic score to then being part of stratification for modern metastatic kidney cancer trials.

🎙️IMDC now shapes what drugs we give for 1st line metastatic kidney cancer.

🙌🏽Kidney cancer survivals have quadrupled since the early Interferon era

💡We discuss biomarkers 🧭

💡We discuss more biomarkers - KIM 1, Clusters, Composite Biomarkers.

This was so much fun to record and an absolute privilege to have Danny on the Podcast🙌🏽

☀️ Enjoy ☀️

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Join us as we complete our discussion on all things Acute Oncology Services with the superb Dr Caroline Wilson PhD FRCP from the The Christie NHS Foundation Trust.

🎙️We look at what future directions AOS will move into and what the challenges may be.
🎙️What are the BIG 5 AOS presentations?
🎙️Caroline stacks a claim for the need to change how we view the role of who manages acute oncology toxicities.

Enjoy

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Welcome back - today we are discussing Acute Oncology Services and how they have evolved over the last 15 years.

Why were they set up ?

To give cancer patients support and care when they need it most - when they are admitted to hospital with problems.

Do you know your type 1 from your type 2 or 3 Acute oncology patient?

We talk all things AOS with the wonderful Dr Caroline Wilson from The Christie Hospital in Manchester.

What would your ideal Acute Oncology Service look like? Caroline tells us how she is building her new service.

Is yours the same as ours - probably not?

Do we need to loosen the oncology strings on SACT toxicity and encourage this to be a general medical issue.

All this and more - Enjoy!

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Welcome back to part 2 of our 2 part special on the INTENSIFY trail in metastatic prostate cancer study. We welcome back the wonder Professor Simon Crabb and Dr Sarah Chamberlain from the University Hospital Southampton where they work n the medical oncology department treating urological cancers.

If you haven’t listened to part 1 please go check it out now where we set the foundations of the INTENSIFY trial.

Now lets get in to the science behind the INTENSIFY study looking at eh DECIPHER score and pTEN.

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Welcome to the Simply Oncology Podcast.

Today we are focusing in on the prostate cancer trial called INTENSIFY.

This is a trial where we will look at intensifying metastatic prostate cancer patients.

Those patients established on combination LHRHa and ARPi therapy could then be randomised at 6months to adding chemotherapy or not if they don't have an optimal PSA tumour marker improvement.

We have brought the wonderful Professor Simon Crabb, and Dr Sarah Chamberlain from the oncology team at Southampton. They are part of the leadership team for the trial.

This trial is already running in some centres and we discuss why it is happening and how it would be delivered.

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Welcome back to part 2 of this episode on radiotherapy in muscle invasive bladder cancer where we explore the challenging questions of equitable access to neoadjuvant and adjuvant novel therapies in patients not suitable for cystectomy.

We welcome back the brilliant Dr Mohini Varughese, fighting the good fight for bladder preservation treatment!

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Welcome back!

🎙️We dive back in to the exciting and dynamic world of systemic therapy in localised muscle invasive bladder cancer

🔦Shining a spotlight on bladder preservation treatment ie: radiotherapy with a radiosensitiser, a key player in the curative treatment of this cancer.

🤷Is Radiotherapy at risk of being left behind with recent trials improving neoadjuvant and adjuvant systemic therapies with trials that have focussed exclusively on cystectomy.

🎙️We welcome back Dr Mohini Varughese from Royal Devon University Hospitals to take on this important topic in a 2 part episode!

🎙️What is the Real World Landscape like and how many people are having radiotherapy for muscle invasive bladder cancer??

All this and more!