AI transformation in healthcare isn't something happening to physicians—it's an evolution physicians can actively shape and lead.

In this episode, we introduce our host, Dr. Junaid Kalia, a practicing neurologist who experienced healthcare's systemic failures firsthand and decided to build the solution himself. As founder of SaveLife.AI, his journey embodies physician-led innovation: combining clinical expertise with entrepreneurial action to create real transformation. Joining the conversation are his sister, Dr. Saira Kalia (academic program director), and close friend, Dr. Danish Bhatti (angel investor/advisor), as they discuss the evolution from clinician to innovator—and why "action bias" matters more than perfect planning.

Join our panel of a private sector entrepreneur, an academic program director, and an angel investor/advisor for a peer-to-peer reality check on the barriers, breakthroughs, and lessons learned.

What You Will Discover:

- Meet the Panel: Neurologist, Psychiatrist, and Their Unconventional Journeys

- Why They Stepped Outside the Traditional Clinical Pathway

- The Reality of Physician-Entrepreneurship

- Reason Behind Execution Failure

- The Resistance & Barriers They Didn’t Expect

Connect with us:

Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

🔗Website - https://www.junaidkalia.com/

📹YouTube - https://www.youtube.com/@junaidkaliamd

Dr. Harvey Castro, ER Physician, #DrGPT™

💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

🔗Website - https://www.harveycastromd.com/

📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

Edward Marx, CEO, Advisor

💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

🔗Website - https://www.marxadvisory.com/

📹YouTube - https://www.youtube.com/@EdwardMarx

Special Guest:

Saira Kalia, MD, Associate Professor, Arizona & Pediatric & Perinatal Psychiatry

💼LinkedIn - https://www.linkedin.com/in/saira-kalia-md-60685a132/overlay/about-this-profile/

Danish Bhatti, MD, Serial Entrepreneur and Angel Investor in Healthcare Startups

💼LinkedIn - https://www.linkedin.com/in/danish-bhatti/

Visit our website:

https://signalandsymptoms.com/

Get advisory insights about Healthcare AI — at zero cost:

https://junaidkaliamd.substack.com/

Drug development today forces patients to fit standard medications—but what if we could reverse that paradigm and design treatments tailored to each patient's unique biology?

This episode explores how specialized AI cloud infrastructure is transforming drug discovery and healthcare research–not as a distant future possibility, but as tools available to researchers today. Joining the conversation is Dr. Ilya Burkov, who shares how the right computational foundation and HPC tools accelerate scientific breakthroughs at AI speed.

The conversation reveals a significant shift in accessibility: junior researchers without specialized training now achieve 80-90% success rates in complex CRISPR experiments using agentic AI systems. These results once required years of expertise. Small research teams and startups can now access the same cutting-edge infrastructure as major pharmaceutical companies. This democratization directly impacts clinical practice: drug development timelines are compressing from decades to months, which means personalized treatments tailored to individual biology could become available within your career timeline.

It's not just about raw infrastructure efficiency. It's about the combination of technology, accessibility, domain expertise, and white-glove support that together transform what's possible in healthcare innovation.

What You Will Discover:

- Dr. Burkov: Bridging Biology and AI Infrastructure

- Nebius: AI Cloud for Drug Discovery, Genomics, Health Tech

- Scaling Personalized Patient Medicine

- Expert Support vs. Generic Clouds

- AI Success for Junior Researchers

- AI in Drug Discovery

- Nebius On Democratizing Latest GPU Access

- Future: Predicting Individual Patient Outcomes

Referenced in the show:

🖇️ "CRISPR-GPT for agentic automation of gene-editing experiments" – https://pubmed.ncbi.nlm.nih.gov/40738974/

Connect with us:

Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

🔗Website - https://www.junaidkalia.com/

📹YouTube - https://www.youtube.com/@junaidkaliamd

Dr. Harvey Castro, ER Physician, #DrGPT™

💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

🔗Website - https://www.harveycastromd.com/

📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

Edward Marx, CEO, Advisor

💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

🔗Website - https://www.marxadvisory.com/

📹YouTube - https://www.youtube.com/@EdwardMarx

Special Guest:

Dr. Ilya Burkov, Global Head of Healthcare & Lifesciences at Nebius

💼LinkedIn -

The most dangerous assumption in healthcare AI today is that we have time to "wait and see" how tools develop. With the state-of-the-art for AI models now shifting every 7 days, the traditional 3-year implementation cycle isn't just slow—it’s stagnating clinical transformation.

In this episode, Dr. Khan Siddiqui (Radiologist and Founder of Hoppr AI) joins the panel to reveal why the future of medicine isn’t about choosing the "perfect" tool. Instead, it’s about building a sustainable system that can keep pace with technology improving at 1,600 times the speed of human practice.

This conversation moves beyond theory to address a raw, systemic crisis facing modern medicine: where radiologists must read 145 cardiac CT scans in a single shift—roughly 5.5 images per second. This unsustainable pace leaves physicians exhausted and their families suffering the collateral damage of clinical burnout.

Dr. Siddiqui breaks down how the collision of massive workforce shortages and declining reimbursements has moved AI from a "luxury" to a baseline requirement for survival. To meet this challenge, the episode explores the critical shift in a clinician-led innovation, frictionless workflow, and dynamic regulation.

What You Will Discover:

- From Clinician to AI Visionary

- The Microsoft Origin of Hoppr

- The True Cost of Clinical Burnout

- The Systemic Collapse: Workforce Gaps

- Why Augmentation is Survival

- Ending Static AI Governance

- Dr. Siddiqui’s Vision for the Future of Medicine

- AI Without the Tech Tax

- Why the FDA Model is Failing

Connect with us:

Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

🔗Website - https://www.junaidkalia.com/

📹YouTube - https://www.youtube.com/@junaidkaliamd

Dr. Harvey Castro, ER Physician, #DrGPT™

💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

🔗Website - https://www.harveycastromd.com/

📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

Edward Marx, CEO, Advisor

💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

🔗Website - https://www.marxadvisory.com/

📹YouTube - https://www.youtube.com/@EdwardMarx

Special Guest:

Khan Siddiqui, MD, Radiologist, Founder of HOPPR

💼LinkedIn - https://www.linkedin.com/in/khansiddiqui/

🏥Hoppr AI - ​​https://www.hoppr.ai/

Visit our website:

https://signalandsymptoms.com/

Get advisory insights about Healthcare AI — at zero cost: