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Signal and Symptoms Podcast

Signal and Symptoms Podcast

By: Harvey Castro MD Junaid Kalia MD & Edward Marx
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 Three healthcare AI experts who've watched millions wasted on failed projects. Dr. Harvey Castro, Dr. Junaid Kalia, Edward Marx, and guest experts cover all things healthcare AI - from digital transformation to clinical reality. Every Tuesday, we diagnose real failures, reveal what actually works, and help you avoid the expensive mistakes we've seen repeated everywhere. Because when AI decisions affect patient care, getting it right isn't optional.Copyright 2026 Harvey Castro MD, Junaid Kalia MD, & Edward Marx Hygiene & Healthy Living Physical Illness & Disease Politics & Government
Episodes
  • The Business Playbook for Physicians Who Want to Win Beyond the Clinic

    The Business Playbook for Physicians Who Want to Win Beyond the Clinic
    Apr 21 2026

    You went into medicine to save lives. But somewhere between residency and the real world, you started wondering — is there more I could be doing?

    That question is not a distraction. It might be your next diagnosis, and the biggest obstacle is knowing where to start.

    In this episode, host Dr. Junaid Kalia sits down with Dr. Sara Rana, a physician-turned-venture capitalist and MD-MBA, who saw the gap between healthcare and finance firsthand and built her career bridging it. The conversation moves from her origin story into the practical frameworks, honest realities, and hard-earned wisdom any physician can act on today.

    What You Will Discover:

    - Intro: Dr. Sara’s Origin Story

    - Why Physicians Must Speak Business

    - Charting Her Own Path as Venture Capitalist

    - Inflation, AI & the Forces Reshaping Financial Future

    - Does Race & Gender Matter?

    - 4 Entry Points to Entrepreneurship

    - The Advice That Reframes the Struggle

    [17:23] Does Geography Make or Break You?

    The same disruption reshaping healthcare through AI is exactly why physicians can no longer afford to only speak medicine. This conversation is where that journey begins.

    Connect with us:

    Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™

    💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd

    🔗Website - https://www.junaidkalia.com/

    📹YouTube - https://www.youtube.com/@junaidkaliamd

    Dr. Harvey Castro, ER Physician, #DrGPT™

    💼LinkedIn - https://www.linkedin.com/in/harveycastromd/

    🔗Website - https://www.harveycastromd.com/

    📷Instagram - https://www.instagram.com/harveycastromd/?hl=en

    📑 Substack - https://harveycastromd.substack.com/

    Edward Marx, CEO, Advisor

    💼LinkedIn - https://www.linkedin.com/in/edwardmarx/

    🔗Website - https://www.marxadvisory.com/

    📹YouTube - https://www.youtube.com/@EdwardMarx

    Special Guest:

    Sara Rana, MD, MBA

    💼LinkedIn - https://www.linkedin.com/in/sararana/

    Visit our website:

    https://signalandsymptoms.com/

    Get advisory insights about Healthcare AI — at zero cost:

    https://junaidkaliamd.substack.com/

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    20 mins
  • How Ultrasound Frequencies Enable Early Intervention and Save Lives

    How Ultrasound Frequencies Enable Early Intervention and Save Lives
    Apr 14 2026
    What if the difference between a late diagnosis and a successful intervention was simply how we decode the signals of a sound wave?In this episode, we are discussing the transition of ultrasound from a static hospital tool to a mobile network of care that brings diagnostics directly to the patient. Dr. Junaid Kalia, Dr. Harvey Castro, and Edward Marx explore a radical shift in medical imaging with Soner, Co-founder and CEO of PONS Tech. By analyzing raw ultrasound frequencies rather than just the visual image, PONS makes visible the early-stage features that are typically invisible on a standard scan. This episode breaks down how we can empower non-specialists—like nurses and caregivers—to perform expert-level scans without disrupting the radiologist's existing workflow.From navigating clinical "dyad" leadership to addressing the financial barriers of the current revenue cycle, we map out how to rebuild a reactive healthcare system into a proactive, community-based signal of care.What You Will Discover:Intro: From Personal Tragedy to a Medical Innovation- Why PONS Focuses on Raw Frequency-Level Dynamics- How the Tech is Scaling Diagnostic Accuracy - On Addressing the Limitations of Mammography- Why Health Systems Must Rethink How We Pay for Prevention- Shifting Health Systems Toward Continuous Preventive Care🎤 Host Spotlight: Ed Marx is keynoting the Northwood University Health Care Summit on April 22. Worth a watch — register here: https://lnkd.in/gSi82Zd8Connect with us:Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd🔗Website - https://www.junaidkalia.com/📹YouTube - https://www.youtube.com/@junaidkaliamdDr. Harvey Castro, ER Physician, #DrGPT™💼LinkedIn - https://www.linkedin.com/in/harveycastromd/🔗Website - https://www.harveycastromd.com/📷Instagram - https://www.instagram.com/harveycastromd/?hl=en📑 Substack - https://harveycastromd.substack.com/Edward Marx, CEO, Advisor💼LinkedIn - https://www.linkedin.com/in/edwardmarx/🔗Website - https://www.marxadvisory.com/📹YouTube - https://www.youtube.com/@EdwardMarxSpecial Guest:Soner Hacıhaliloğlu, Co-Founder and CEO of PONS💼LinkedIn - https://www.linkedin.com/in/sonerhaci/Visit our website:https://signalandsymptoms.com/Get advisory insights about Healthcare AI — at zero cost:https://junaidkaliamd.substack.com/
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    18 mins
  • The Treatment Exists But Why Aren't Patients Getting It?

    The Treatment Exists But Why Aren't Patients Getting It?
    Mar 31 2026
    What if the real barrier to better patient outcomes isn't the medicine — it's the infrastructure to prescribe it well?This episode surfaces a broader signal: personalized medicine is no longer a future ambition — it's a present clinical need. And the system, as it stands, is not equipped to deliver it at scale.Joining the conversation are Itay Segal and Dr. Jean-Claude, co-founders of Unlock Healthcare, to explore one of medicine's most underexamined tensions: the gap between what a treatment can do and what the current system is built to support. The discussion centers on cannabinoid medicine — not as a cultural phenomenon, but as a clinical case study for why one-size-fits-all care fails the patients who need personalized treatment most.This episode asks the harder question: before we can treat patients better, do we have the right foundation in place to even try?What You Will Discover:- The Gap Between Need and Treatment- Infrastructure as the Real Innovation- Why One Size Fits No One- The Physician as Informed Partner, Not Just Licensor- The Regulatory Runway- The Evidence GapA note from Signal & SymptomsThis episode doesn't center on AI — and that's precisely the point. Before AI can meaningfully improve patient outcomes, the clinical infrastructure to capture, act on, and learn from patient data has to exist first. What Unlock Healthcare is building is that foundation layer. We separate signal from noise at Signal & Symptoms, and this episode's signal is clear: the future of treatment depends as much on the systems we build around medicine as on the medicine itself.References:🖇️ "DRGPT AI Lessons (3 books)" – https://www.amazon.com/dp/B0GTNQ18K2?binding=paperbackConnect with us:Dr. Junaid Kalia, Neurocritical Care Specialist and Founder of Savelife.AI™💼LinkedIn - https://www.linkedin.com/in/junaidkaliamd 🔗Website - https://www.junaidkalia.com/ 📹YouTube - https://www.youtube.com/@junaidkaliamd Dr. Harvey Castro, ER Physician, #DrGPT™💼LinkedIn - https://www.linkedin.com/in/harveycastromd/ 🔗Website - https://www.harveycastromd.com/ 📷Instagram - https://www.instagram.com/harveycastromd/?hl=en 📑 Substack - https://harveycastromd.substack.com/ Edward Marx, CEO, Advisor 💼LinkedIn - https://www.linkedin.com/in/edwardmarx/ 🔗Website - https://www.marxadvisory.com/ 📹YouTube - https://www.youtube.com/@EdwardMarx Special Guests:Itay Segal, Co-Founder, CEO at Unlock.Healthcare💼LinkedIn - https://www.linkedin.com/in/itay-segal-723b488/Jean Claude Scicluna, MD, MSc, Co-Founder, Medical Director at Unlock.Healthcare💼LinkedIn - https://www.linkedin.com/in/jeanclaudescicluna/ Visit our website:https://signalandsymptoms.com/Get advisory insights about Healthcare AI — at zero cost:https://junaidkaliamd.substack.com/
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    20 mins
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