I'm joined by Dr Nick Fuller to dissect the long-term effectiveness of weight loss medications and why lasting results do actually require more than medication alone.

Nick explains why evidence-based behavioural weight management programs remain the first-line approach to weight loss built on three key pillars: diet, exercise and sleep (did you even know that sleep plays a big role in regulating hunger hormones?!)

Drawing on his team's research, Nick shares why many people regain weight after stopping medication and why behavioural change is essential for sustainable success (and keeping weight off for good!)

This episode I'm joined by Dr Peter Lee, Head of Research at Microsoft, to explore the ideas shaping the future of technology. Leading 14 research laboratories globally and overseeing a research and development program that receives more than 10% of Microsoft's overall budget, Dr Lee shares his journey to the top of one of the world's largest innovation engines.

From AI tools transforming early cancer detection and predicting protein structures in hours (instead of years!), to discovering new battery materials and improving weather forecasting through deep learning, the conversation reveals how research is moving from possibility to real-world impact. We also explore Microsoft's investment in open-ended innovation, research not driven by immediate products, but by imagining entirely new experiences and technologies.

Encrypted Spaces - Microsoft Research | Microsoft Research

In this episode, we speak with Dietmar Müller about the "Boring Billion", a seemingly quiet period in Earth's deep history that may have been crucial for the evolution of complex life. Drawing on his latest research, Müller explains how plate tectonics, passive continental margins, and volcanic outgassing shaped Earth's slow carbon cycle and gradually oxygenated the oceans during the mid-Proterozoic era.

Müller also reflects on how young the science of plate tectonics really is, and discusses the open-source EarthByte tools his team at the University of Sydney has developed to model Earth's ancient geological past.

www.earthbyte.org/