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Once a Scientist

Once a Scientist

By: Nick Edwards
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Unfiltered career discussions with scientists© 2026 Once a Scientist Science
Episodes
  • 93. Jason Kelly, CEO and co-founder of Ginkgo Bioworks, on the future of autonomous laboratories
    Feb 25 2026

    Episode 93. Jason Kelly is the co-founder and CEO of Ginkgo Bioworks. He has a Ph.D. in Biological Engineering and a B.S. in Chemical Engineering and Biology from the Massachusetts Institute of Technology.

    References:

    https://www.ginkgo.bio/autonomous-lab

    OUTLINE:
    00:00 – From Jurassic Park Pilled to MIT
    03:00 – Founding Ginkgo During the 2008 Crash
    07:00 – Tom Knight & Thinking About Biology Like Software
    11:00 – Why Biology Lacked Abstraction (Until Now)
    16:00 – The Foundry Model: Centralizing Biology
    20:00 – The 5 Levels of Lab Automation
    23:00 – Automation vs. Autonomy (Subway vs. Waymo)
    27:00 – The Technical Bottleneck: Connecting 150+ Machines
    34:30 – The Zymergen Acquisition & Strategic Pivot
    38:00 – Level 4 & 5 Labs: The Future of Programmable Biology

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    42 mins
  • 92. Ashlee Vance, tech reporter and filmmaker, on storytelling, science funding, and interviewing billionaires
    Jul 23 2025

    Episode 92. Ashlee Vance is a renowned tech and science reporter, filmmaker, and founder of Core Memory, a podcast and blog that chronicles the lives and discoveries of scientists and engineers (https://www.corememory.com/). He wrote the definitive biography on Elon Musk and has been documenting the modern space race and recent developments in AI, among other things.

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    1 hr and 2 mins
  • 91. Michael Koeris, Director of DARPA BTO, on autonomous science to accelerate discovery
    Apr 23 2025

    Episode 91. Michael Koeris is the Director of the Biotechnologies Office at DARPA. Michael completed his PhD at Boston University and did postdoctoral research in synthetic biology at MIT. He spent time early in his career at Flagship Pioneering, is a former founder and executive of multiple biotechs, and was formerly a professor at the Keck Graduate Institute.

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    55 mins
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