This release contains only the music track from Base by Base Episode 398.

Song title: Not Just the Slope
Original Base by Base episode: 398: Modeling JAK2V617F Clonal Expansion in the General Population

Article metadata:
Article title: Mathematical modeling of JAK2V617F clonal expansion in a general population cohort
Journal: Proceedings of the National Academy of Sciences (PNAS)
DOI: 10.1073/pnas.2507773123
Reference: Snyder J, Andersen M, Gudmand-Høyer J, et al. Mathematical modeling of JAK2V617F clonal expansion in a general population cohort. Proc Natl Acad Sci U.S.A. 2026;123:e2507773123. doi:10.1073/pnas.2507773123

Lyrics:
Verse 1
In the quiet bloodline under neon light,
A tiny spark can lean to wrong or right.
Same red numbers on a paper screen,
But different forces in the in-between.

Pre-Chorus
One step forward, one step back in time,
Chance and pressure in a hidden rhyme.
We watch the fraction rise, or stall, or fade,
And wonder what the stem cells chose and made.

Chorus
It’s not just the slope, not just the climb,
Not every signal means the end in time.
A thousand silent turns beneath the skin,
Where drift can lose, or selection can win.
So hold that line, read deeper than the chart—
The future starts in the smallest part.

Verse 2
Some carry storms that never break the day,
Some feel the current pulling hard one way.
A crowded pool where every copy fights,
A coin-flip kingdom counting days and nights.

Bridge
If we can name the edge you’re standing on,
We can listen sooner, long before it’s gone.
Not prophecy—just math with room for doubt,
A map of how a single clone plays out.

Final Chorus
It’s not just the slope, not just the climb,
Not every shadow means the end in time.
A thousand silent turns beneath the skin,
Where drift can lose, or selection can win.
So keep the watch, let patience do its part—
The warning whispers, and the hope can start.

• (00:00:24) - A Single Clone's Story