What is the most sustainable catheter we could design from scratch today?

Damian Carr, founder of Eyedea MedTech Education and author of the Catheter R&D Handbook, joins me for a full case study. We break down how catheters are built today, why the process is still manual and fluoropolymer-heavy, and what a modern reel-to-reel line would look like.

We cover PFAS-free liners, UHMWPE, dynamic co-extrusion, same-polymer designs that can be recycled, and the cost reality: 20 to 25% of today's cost at five times the output once the line runs. Damian is clear that there is no one-to-one replacement for fluoropolymers, so the job is to match the property the application actually needs.

We also talk about the human side. The "point of no return" in the operating room, and why engineers need to sit with surgeons before they design the next device.

This episode is sponsored by Masterflex Group.
Masterflex | Schlauchhersteller | Schläuche und Verbindungen

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

Can bio-based plastic move past the nice story and scale in regulated MedTech?

Tim Wagler is Commercial Director EMEA for Braskem's I'm green bio-based portfolio, polyethylene made from sugarcane instead of fossil feedstock. Braskem just launched an I'm green bio-based medical grade.

In this episode:
- What "physical content" bio-based means and how it differs from mass balance
- Why fossil prices are spiking and bio-based is no longer the expensive option
- The supply and land-use question, and why sugarcane uses 0.03% of Brazil's land today
- Why bio-based is not biodegradable, and the claims you can actually make
- Where a drop-in bio-based polyethylene fits in medical and pharma

CONNECT WITH TIM
Tim Wagler: https://www.linkedin.com/in/tim-wagler-891436a4/
Braskem I'm green: https://www.braskem.com/imgreen/landingpage

ABOUT THE PODCAST
MedTech Sustainability by Design is the Gradical podcast on choosing better plastics and building better medical devices.
Book a free consultation: https://calendly.com/lucas-pianegonda-gradical/discovery-call-gradical
Gradical: https://www.gradical.ch

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

How does a company with 120,000 colleagues and 500,000 products put a number on its carbon footprint and actually act on it?

Matthew Yamatin is Global Director Sustainability at Thermo Fisher Scientific. He built the corporate sustainability program from scratch after joining in 2022 and now runs it across eight business groups.

In this episode:

- The scalable method Thermo Fisher uses to calculate product carbon footprints across half a million products

- Why mass balance is the only realistic path to non-fossil plastics in a regulated industry

- How biogenic carbon accounting actually works, and where the greenwashing debate sits

- Why bio-based plastics stay tied to the oil price, and what it takes to decouple them

- How to keep a sustainability program simple enough to move

If you work in sustainability, procurement, or product development in life sciences or medtech, this gives you a model you can copy.

Connect with Matthew: https://www.linkedin.com/in/matthewyamatin/

Thermo Fisher Scientific: https://www.thermofisher.com

00:00 How a 120,000-person company tackles sustainability at scale

01:16 The shampoo aisle problem

06:21 Inside Thermo Fisher

12:43 Scope 1, 2, 3 and the GHG Protocol

15:23 PCF vs CCF

17:50 The scalable PCF method

24:21 Why mass balance is the only scalable path

30:27 Biogenic carbon explained

40:59 Why bio-based costs more

44:10 Building a program from scratch

49:33 Find your North Star KPI

55:14 Closing

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

"Do not do ego-design." A professor told Bart Verleije that in school, and it shaped how he has built medical devices ever since.

Bart is Commercial Director at Voxdale, a Belgian design and engineering firm, with more than 1,400 projects over 19 years. He explains how a napkin sketch becomes a certified, manufacturable device, and where most MedTech projects go wrong before they reach a patient.

In this episode:

- His BURST framework: Business, User, Regulatory, Sustainability, Technology

- Why design for manufacturability has to start on day one

- How to stop feature creep and trade off conflicting requirements

- The Ergotrics story: an inflatable system for turning and proning patients

If you develop devices, this one will change how you scope your next project.

Connect with Bart: https://www.linkedin.com/in/bartverleije/

Voxdale: https://www.voxdale.be

00:00 From a napkin sketch to a certified device

00:56 Meet Bart Verleije: 1,400+ projects, 19 years at Voxdale

01:45 Commit to your product before you build it

05:05 "Do not do ego-design"

06:42 Why every stakeholder needs at least a neutral stance

09:56 The BURST framework: Business, User, Regulatory, Sustainability, Technology

15:46 Design for manufacturability from day one

20:30 The operational cost teams overlook

23:20 A healthy take on AI in documentation

28:29 Database-first documentation and regulation as code

30:13 The conservation of misery: trading off requirements

34:04 Only five value drivers make the board

37:28 "How do you know this?" Breaking false requirements

40:11 Over-requirement is the biggest cost driver

41:33 From a highway traffic jam to proning patients

45:10 The toothpaste factory and the 20-dollar fan

48:17 Bart's advice: commit, talk to experts, stay in your lane

55:28 Closing

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

Most sustainable plastics cost two to six times more than oil-based alternatives. That's why you don't see them everywhere. Alex Braun decided to fix that.

Alex is the Chairman of Pillar Ltd, an Israeli industrial R&D company with 26 years of experience building materials for the world's largest manufacturers. Out of that work came three startups: PlasticBack, which chemically recycles PVC at under 100 degrees Celsius. Snow Polymers, which makes bio-based plastic at oil prices without requiring new machinery. And Inteligels, a smart wound care polymer that washes off with cold water instead of being peeled off a burn.

Here's what we get into:

• Why most sustainable plastics fail commercially before they ever reach the market
• How Snow Polymers makes bio-based plastic price-competitive with fossil fuels using industrial waste as feedstock
• Why PVC is the fourth-largest plastic produced but the last to be recycled, and what PlasticBack does about it
• How Inteligels eliminates the most painful procedure in hospitals
• The R&D model that lets Pillar Ltd take risks that neither startups nor corporates can

This episode is sponsored by Pillar Ltd.

If you want to make your products more sustainable, let's talk: https://calendly.com/lucas-pianegonda-gradical/discovery-call-gradical

🔗 CONNECT WITH Pillar Ltd: https://www.Pillar Ltd-ltd.com/about-us

🔗 CONNECT WITH US:
🎧 Apple Podcasts – https://podcasts.apple.com/us/podcast/gradical-podcast-the-podcast-about-plastics-in/id1773569554
🟢 Spotify – https://open.spotify.com/show/4vNQ6rPE2CQUGgQtEY3sYq
📺 YouTube – https://www.youtube.com/@GradicalGmbH
🌍 Gradical: https://gradical.ch/
📩 Work with us: lucas.pianegonda@gradical.ch

#MedTechSustainabilityByDesign #GradicalPodcast #SustainablePlastics #Bioplastics #ChemicalRecycling #PVC #WoundCare #DeepTech #MaterialScience

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

Over a billion autoinjectors are used every year. Almost all of them are single-use. Almost all of that plastic gets incinerated.

John Palmer-Felgate spent 30 years designing medical devices. At some point, he decided to actually fix the problem.

John is the Founder and CTO of Eco-Inject, a UK startup that has built a sustainable autoinjector from the ground up using 100% bio-based polymers, fewer components, and a completely rethought internal architecture.

Here's what we get into:

• Why you can't just swap in sustainable materials and call it a day
• How John reduced the device to five simple plastic moldings
• Why the production line footprint is a quarter of the current standard
• How Eco-Inject achieves a lower cost of goods and better sustainability at the same time
• The commercial reality of selling sustainability to pharma procurement

This episode is sponsored by Eco-Inject.

If you want to make your medical devices more sustainable, let's talk: https://calendly.com/lucas-pianegonda-gradical/discovery-call-gradical

🔗 CONNECT WITH JOHN PALMER-FELGATE: https://www.linkedin.com/in/john-palmer-felgate/

🔗 CONNECT WITH ECO-INJECT: https://www.linkedin.com/company/eco-inject/posts/?feedView=all

🔗 CONNECT WITH US:
🎧 Apple Podcasts – https://podcasts.apple.com/us/podcast/gradical-podcast-the-podcast-about-plastics-in/id1773569554
🟢 Spotify – https://open.spotify.com/show/4vNQ6rPE2CQUGgQtEY3sYq
📺 YouTube – https://www.youtube.com/@GradicalGmbH
🌍 Gradical: https://gradical.ch/
📩 Work with us: lucas.pianegonda@gradical.ch

#MedTechSustainabilityByDesignPodcast #GradicalPodcast #MedTech #AutoInjector #SustainableDesign #MedicalDevices #Bioplastics #DrugDelivery

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

A lot of MedTech companies treat CAPA as a compliance exercise. They open a record, close a record, and survive the audit. Georg Digel has spent his career watching what happens when that's the only goal… and it's not pretty.

Georg is the Founder and Owner of Elevate CAPA. He has spent years helping MedTech companies build CAPA systems that actually work: ones that identify real problems, trace them to their root cause, and prevent them from coming back.

Here's what we get into:

• Why CAPA is one of the most misunderstood processes in medical technology
• The difference between a non-conformity and a CAPA
• What auditors actually find when they inspect CAPA systems
• Why "death by CAPA" happens and how to avoid it
• How management culture makes or breaks the whole thing
• What a lean, functional CAPA process looks like in practice

🔗 CONNECT WITH GEORG DIGEL: https://www.linkedin.com/in/georgdigel/?locale=de

🔗 CONNECT WITH US:
🎧 Apple Podcasts – https://podcasts.apple.com/us/podcast/gradical-podcast-the-podcast-about-plastics-in/id1773569554
🟢 Spotify – https://open.spotify.com/show/4vNQ6rPE2CQUGgQtEY3sYq
📺 YouTube – https://www.youtube.com/@GradicalGmbH
🌍 Gradical: https://gradical.ch/
📩 Work with us: lucas.pianegonda@gradical.ch

#MedTechSustainabilityByDesignPodcast #GradicalPodcast #MedTech #CAPA #QualityManagement #MedicalDevices #ContinuousImprovement #QMS #Compliance

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch

This episode is brought to you by Vanguard, a company specializing in remanufacturing single-use medical devices to as-good-as-new condition.

A device labeled "single-use" gets thrown away after one patient. That makes sense for a syringe. It makes a lot less sense for a cardiac catheter that costs thousands of euros.

Ulrike Marczak is the CEO of Vanguard, a company that has been remanufacturing complex single-use medical devices for 30 years. They take used devices from hospitals, fully refurbish them, put their own CE mark on them, and send them back. Safe, legal, and up to 50% cheaper for the hospital.

Here's what we get into:

• The difference between reprocessing and remanufacturing
• Why remanufacturing makes sense economically, ecologically, and operationally for certain devices
• How Vanguard tests every single device 100%
• Which devices are good candidates, and where the business case breaks down
• What OEM manufacturers should be thinking about when they design for the future

If you want to make your medical devices more sustainable, let's talk: https://calendly.com/lucas-pianegonda-gradical/discovery-call-gradical

🔗 CONNECT WITH ULRIKE MARCZAK:

Vanguard: https://www.vanguard.de/vanguard-ag/

LinkedIn: https://www.linkedin.com/in/ulrike-marczak-138045115/

🔗 CONNECT WITH US:

🎧 Apple Podcasts – https://podcasts.apple.com/us/podcast/gradical-podcast-the-podcast-about-plastics-in/id1773569554

🟢 Spotify – https://open.spotify.com/show/4vNQ6rPE2CQUGgQtEY3sYq

📺 YouTube – https://www.youtube.com/@GradicalGmbH

🌍 Gradical: https://gradical.ch/

📩 Work with us: lucas.pianegonda@gradical.ch

#MedtechSustainabilityByDesignPodcast #GradicalPodcast #MedTech #CircularEconomy #SingleUse #Remanufacturing #MedicalDevices #Sustainability #HealthcareInnovation

Do you enjoy this podcast? Then subscribe, rate it on your platform, and join the discussion on LinkedIn! Your feedback and comments help us improve the podcast and bring you relevant topics. Let’s form a better world with plastics!

If you are a Medtech company struggling to make your devices more sustainable, let’s talk—BOOK A CALL HERE.

You can also check our Youtube Channel with lots of free trainings and resources here: Lucas R. Pianegonda - YouTube

Website: www.gradical.ch