Episodes

  • Increasing Productivity in Clinical Research - Life Sciences Today Podcast Episode 48

    Increasing Productivity in Clinical Research - Life Sciences Today Podcast Episode 48
    Feb 13 2026

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Zina Sarif, Founder and CEO at Yendou.

    Zina Sarif is one of the most dynamic and inspirational founders I’ve met. She grew up in Morocco until age 20 and, after her PhD in biology, spent a decade in cancer drug discovery before leading clinical research at Parexel and PhIII oncology trials at AstraZeneca. Driven by the vision of a cancer-free world, she built Yendou to accelerate research, streamline site operations, and deliver life-saving treatments faster.

    Yendou streamlines the site selection process and the interaction between CROs, sponsors, and sites, producing 2X improvements in productivity. One of my other guests from Lindus Health said it best, “Everyone is more productive with Yendou. We accelerated feasibility timelines by 50% while reducing manual follow-ups by 70%.”

    Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

    • Tell us about your personal journey—how did you get from consulting and Viva to leading Ledger Run?
    • Who are your customers, and what specific problems are you solving for them?
    • How do you create value for sponsors and CROs in clinical trial site selection and relationship management?
    • How do you capture that value—what does your business/revenue model look like?
    • What is the biggest anti–design pattern you see in the industry right now?

    Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

    Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

    Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

    • Apple Podcasts
    • Spotify
    • iHeartRadio
    • Amazon Music
    • Pandora
    • YouTube

    Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

    If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

    Thanks so much for listening!
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    37 mins
  • Payments, Pain, and Pragmatic AI in Clinical Trials - Life Sciences Today Podcast Episode 47

    Payments, Pain, and Pragmatic AI in Clinical Trials - Life Sciences Today Podcast Episode 47
    Feb 6 2026

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is John Chinnici, CEO at Ledger Run. I talk with Chinnici about his journey from consulting (Andersen, IBM) to Viva, where he helped launch and grow Vault, and eventually to leading Ledger Run. Ledger Run focuses on the “unsexy but critical” operational layer of clinical trials: contracting and paying investigative sites. Chinnici explains how delayed, incorrect, and bureaucratic payments have become an accepted but damaging status quo in clinical research, despite sites running on razor-thin margins.

    Ledger Run’s SaaS platform and services aim to ensure strict contract compliance, dramatically improve operational efficiency, and turn reliable payments into a competitive advantage for sponsors in site recruitment. Chinnici also argues that a major industry anti-pattern is pouring AI investment into volatile early research use cases while underinvesting in high-ROI operational applications such as automating invoice processing and other repetitive payment workflows.

    Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

    • Tell us about your personal journey—how did you get from consulting and Viva to leading Ledger Run?
    • Who are your customers, and what specific problems are you solving for them?
    • How do you create value for sponsors and CROs in clinical trial payments and contracts?
    • How do you capture that value—what does your business/revenue model look like?
    • What are three things you want to do for your customers in the next 12–18 months to make them insanely happy?
    • What is your competitive moat—what makes Ledger Run hard to copy compared with large CROs and other players?
    • What is the biggest anti–design pattern you see in the industry right now?

    Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

    Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

    Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

    • Apple Podcasts
    • Spotify
    • iHeartRadio
    • Amazon Music
    • Pandora
    • YouTube

    Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

    If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

    Thanks so much for listening!
    Show More Show Less
    28 mins
  • Beyond the Science by Gary Zammit - Life Sciences Today Podcast Episode 46

    Beyond the Science by Gary Zammit - Life Sciences Today Podcast Episode 46
    Jan 30 2026
    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Gary Zammit, PhD, President and Chief Executive Officer at Clinilabs. We often imagine medical breakthroughs as the result of data, protocols, and lab science alone. But Gary Zammit has seen firsthand that bringing therapies to patients requires far more: resilient teams, disciplined processes, and cultures that can weather setbacks. In his new book, Beyond the Science: How People, Process, and Systems Transform the Business of Life Sciences, Zammit offers readers an inside look at the real drivers of innovation. From navigating near-bankruptcy at Clinilabs to helping advance more than twenty therapies across thirteen CNS indications, his stories highlight the human and organizational forces that shape the future of medicine. Whether you are in healthcare, business leadership, or organizational strategy, Beyond the Science is both a practical guide and an urgent call to action: to build organizations as resilient and innovative as the science they support because patients are waiting. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: Tell me about your journey. How did that shape you as a leader, and how did those experiences lead you to write Beyond the Science?From your vantage point at Clinilabs, what’s the most misunderstood people-or-process failure in drug development — and how does Clinilabs create value by solving it? How do you prove to sponsors that you’ve actually solved it?CROs often look interchangeable from the outside, yet Clinilabs has built a reputation in one of the most challenging therapeutic areas. Where does your defensibility — your ‘moat’ — really come from? What does Clinilabs do that sponsors or big site networks like Velocity Clinical can’t easily copy?In the closing of the book, you emphasize pushing beyond ‘good enough’ and building teams, systems, and processes that strive for greatness. Looking ahead 12–18 months, what are the three things you want to do for your customers that will raise the bar — things that will materially improve the way CNS trials get run? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple PodcastsSpotifyiHeartRadioAmazon MusicPandoraYouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!
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    Less than 1 minute
  • Almased - Natural Health Superfood Protein - Life Sciences Today Podcast Episode 45

    Almased - Natural Health Superfood Protein - Life Sciences Today Podcast Episode 45
    Jan 23 2026

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guests today are Jamie Luu, RDN, LDN, Strategy and Nutrition Manager, and Ronja Kröger, Nutrition & Product Expert, M. Sc. Nutritional and Food Sciences at Almased. The Almased-type diet can boost natural satiety signals via GLP-1 and PYY — that is real and meaningful. But the new GLP-1-RA drugs go much further: they hijack those same signals, ramp them much higher, and translate into large weight losses in patients with obesity. So the diet is a “natural nudging” of the system; the drugs are a strong “override” of the system.

    Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

    • You’re showing that the Almased high-protein diet raised GLP-1 and PYY levels — how would you compare that to what we know about the injectable GLP-1 drugs (like Ozempic)? Is the mechanism the same, just a different scale, or is there something qualitatively different going on?
    • I read the IIS paper from 2021 and the results are impressive. Given that the diet intervention was isocaloric (same calories) and short-term, yet still changed appetite-hormone profiles — is Almased complementary to GLP-1 drugs like Ozempics or a preventive/maintenance tool for people who aren’t yet eligible for—or don’t want—drugs?
    • For someone who isn’t on GLP-1 medication, what are realistic expectations of using a high-protein total diet replacement in terms of appetite regulation, hormone effects, and perhaps weight maintenance? And how should they view that in the context of the new drug therapies that dominate headlines?

    Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

    Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

    Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

    • Apple Podcasts
    • Spotify
    • iHeartRadio
    • Amazon Music
    • Pandora
    • YouTube

    Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

    If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

    Thanks so much for listening!
    Show More Show Less
    27 mins
  • Clinical Trials with Denali Rose - Life Sciences Today Podcast Episode 44

    Clinical Trials with Denali Rose - Life Sciences Today Podcast Episode 44
    Jan 16 2026

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Denali Rose, VP at Veeva, and Co-Host of Note to File. Rose’s parents are outdoors people and named her after the national park in Alaska. Personally, this is one of the most fun shows we’ve ever done. ‘Nuff said – get in and listen! She is Vice President Sales & Strategy, Site Solutions at Veeva. That’s her day job – she’s also the Co-Host and Producer of the Note To File podcast. She’s focused on delivering solutions for clinical research sites, guiding the sales cycle, and aligning strategy to drive impact and growth. She’s super smart and extremely experienced in the patterns and anti-patterns in the clinical trial industry.

    Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

    • Tell me about your journey.
    • How did you get into podcasting, and why do you think it’s important?
    • CROs are part of the problem, and therefore, they cannot be a part of the solution; sites will inherit the Earth – what is your take on this? Do you think CROs are part of the problem and therefore can’t be part of the solution? Do you think sites will actually inherit the Earth?
    • What other hats do you wear besides ClinOps?

    Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

    Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

    Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

    • Apple Podcasts
    • Spotify
    • iHeartRadio
    • Amazon Music
    • Pandora
    • YouTube

    Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

    If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

    Thanks so much for listening!
    Show More Show Less
    43 mins
  • Data Integrity, Synthetic Data, and Strategic Moats in Healthcare Analytics - Life Sciences Today Podcast Episode 43

    Data Integrity, Synthetic Data, and Strategic Moats in Healthcare Analytics - Life Sciences Today Podcast Episode 43
    Jan 9 2026
    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Daniel Blumenthal, VP of Strategy at MDClone. I talk with MDClone’s VP Strategy about how the company evolved from an early synthetic data pioneer (2016) into a broader data-access and data-extraction platform in a now-crowded market (Snowflake, Oracle, Epic, many synthetic data vendors). Our discussion explores MDClone’s core “nexus” capability of extracting privacy-protected, row-level longitudinal patient data from heterogeneous healthcare systems and producing different types of synthetic data for distinct use cases (research, cross-site collaboration, model development/validation). A major theme is the industry shift from focusing mainly on data access/privacy to treating data integrity and trust as the new frontier and core IP for health systems, pharma, and AI. We debate strategic moats (product vs. project, partnerships vs. competition, where MDClone controls the data supply chain) and how MDClone can remain indispensable as AI and analytics mature. The episode closes with how all this ultimately must translate into better patient outcomes and trustworthy next-generation AI models. Check out the main topics of discussion for this episode of the Life Sciences Today podcast: How has MDClone evolved over the nine years since you became the first employee outside Israel?Synthetic data is now crowded and partially commoditized; what still differentiates MDClone in 2025?In the CIA triad (confidentiality, integrity, availability), is the real new frontier now data integrity rather than access/privacy?What specific part of the healthcare data supply chain does MDClone control that large partners like Snowflake, Epic, or Palantir cannot easily replace?Is MDClone ultimately a product company or a series of bespoke projects, given all the customization and services required?How do you use synthetic data differently for distinct utilities (knowledge gain, cross-site collaboration, model development/validation)?What do you think about trust, privacy, and the patient’s role when patient data is treated as core IP for organizations?How can MDClone help ensure that AI models (including LLMs) are trained and validated on high-integrity, trustworthy data rather than “shitty data”?In a world where every major player can analyze clinical data, what will make MDClone indispensable?How do you see MDClone’s role in directly improving patient outcomes through better data and analytics? Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast. Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business. Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform: Apple PodcastsSpotifyiHeartRadioAmazon MusicPandoraYouTube Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn. If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes. Thanks so much for listening!
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    Less than 1 minute
  • Brain Health, Behavior, and the Future of Dementia Prevention - Life Sciences Today Podcast Episode 42

    Brain Health, Behavior, and the Future of Dementia Prevention - Life Sciences Today Podcast Episode 42
    Jan 2 2026

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is David Bates, Founder and CEO at Linus Health. I talk with David Bates about Linus Health’s mission to transform brain health from late-stage “sick care” to proactive, preventive care. David explains his journey from signal detection research and investing in built-environment technologies to founding Linus Health around the insight that behavior is the primary observable output of the brain. We discuss Linus’s 3-minute digital cognitive assessments that turn rich behavioral signals into thousands of digital biomarkers, enabling highly sensitive, objective measurement of cognition and early detection of impairment years before symptoms. Our conversation covers the company’s focus on primary care and health systems as core customers, revenue and ROI in fee-for-service and value-based care, and Linus’s data moat of large, diverse, longitudinal datasets. We explore how clinically integrated, consumer-accessible tools could make brain health monitoring continuous—like a “blood pressure cuff for the brain”—and why this paradigm shift is critical for both healthcare delivery and drug development.

    Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

    • How did your background in signal detection, multimodal sensing, and investing lead you to found Linus Health?
    • What does Linus Health’s platform actually do, and how are your digital assessments different from traditional paper-based cognitive tests?
    • Who are your main customers today (primary care, health systems, pharma, payers), and how do you create and capture value across these different buyer types?
    • How do you translate thousands of digital biomarkers and AI/ML models into clinically meaningful insights, and how often are your models updated?
    • What is your long-term vision? Is the biggest opportunity in supporting drug development, or in becoming a clinically integrated, mass-market “Internet of bodies” brain health platform for consumers?

    Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

    Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

    Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

    • Apple Podcasts
    • Spotify
    • iHeartRadio
    • Amazon Music
    • Pandora
    • YouTube

    Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

    If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

    Thanks so much for listening!
    Show More Show Less
    40 mins
  • Real-Time Pharma Insights: Philip Poulidis on Scaling ODAIA AI

    Real-Time Pharma Insights: Philip Poulidis on Scaling ODAIA AI
    Dec 26 2025

    We’re excited to be back for another episode of the Life Sciences Today Podcast by Healthcare IT Today. My guest today is Philip Poulidis, CEO at Toronto-based ODAIA. Poulidis is tackling one of pharma’s biggest bottlenecks: slow, siloed commercial analytics. Spun out of academic research, ODAIA’s real-time AI platform unifies patient and HCP journey data, replacing months-old reports with dynamic insights that help reps, liaisons, and marketers target the right physicians at the right time — improving prescriptions, outcomes, and patient access. regulated by the USDA/FDA.

    Check out the main topics of discussion for this episode of the Life Sciences Today podcast:

    • Tell me about your journey.
    • Tell me about ODAIA AI.
    • Who are your customers?
    • How do you create value?
    • How do you capture value from customers?
    • What are three things you want to do for your customers in the next 12-18 months?

    Now, without further ado, we’re excited to share with you the next episode of the Life Sciences Today podcast.

    Subscribe to Danny’s newsletter to get strategic patterns for life science leaders building a defensible business.

    Be sure to subscribe to the Life Sciences Today Podcast on your favorite podcasting platform:

    • Apple Podcasts
    • Spotify
    • iHeartRadio
    • Amazon Music
    • Pandora
    • YouTube

    Along with the popular podcasting platforms above, you can Subscribe to Healthcare IT Today on YouTube. Plus, all of the audio and video versions will be made available to stream on Healthcare IT Today. As a former pharma-tech founder who bootstrapped to exit, I now help TechBio and digital health CEOs grow revenue—by solving the tech, team, and go-to-market problems that stall your progress. If you want a warrior by your side, connect with me on LinkedIn.

    If you work in Life Sciences IT, we’d love to hear where you agree and/or disagree with our takes on health IT innovation in life sciences. Feel free to share your thoughts and perspectives in the comments of this post, in the YouTube comments, or privately on our Contact Us page. Let us know what you think of the podcast and if you have any ideas for future episodes.

    Thanks so much for listening!
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    32 mins