File #010: Fixing the Evidence Engine: Shaun Treweek on Trial Design, Recruitment, and Doing Research Better
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File #010: Fixing the Evidence Engine: Shaun Treweek on Trial Design, Recruitment, and Doing Research Better
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Clinical trials are the backbone of evidence-based medicine—but too often, they struggle with inefficiency, poor recruitment, and avoidable design flaws. In this episode of Clinical Trial Files, we’re joined by Shaun Treweek, Professor of Health Services Research and a leading voice in clinical trial methodology.
Shaun shares his perspective on why so many trials fail to recruit as planned, what the research community gets wrong about trial design, and how embedded studies and methodological research can dramatically improve how trials are run. Drawing from decades of experience across academia, global research collaborations, and methodological innovation, he challenges conventional thinking and advocates for a more evidence-informed approach to doing research itself.
We explore practical ways to make trials more efficient, more ethical, and more likely to deliver meaningful results—while asking a fundamental question: Why don’t we apply the same rigor to how we design trials as we do to the interventions we test?
Whether you’re a researcher, coordinator, sponsor, or policymaker, this episode offers a thoughtful, grounded look at how we can stop repeating the same mistakes and start building better trials from the ground up.