Creatine has been boxed in as a gym-bro supplement for decades, but the latest research shows it's doing far more than building muscle. It buffers brain energy under sleep deprivation, supporting bone density and mood stability through perimenopause, and freeing up methyl groups for detoxification and DNA repair.

We dive deeper into this in the Biohacking Beauty Podcast with Dr. Dan Pardi. We also chat about why the bloating myth is backwards, how creatine and NAD work synergistically to support mitochondrial energy, and what topical creatine could mean for the future of skincare.

Dr. Dan Pardi is a researcher whose first study in the 1990s focused on creatine, and he has spent three decades following the science as it expanded from sports performance into brain health, healthspan, and women's physiology. He is the Chief Health Officer at Qualia Life Sciences, where the team has earned recognition from the Nutrition Business Journal for science and innovation.

His work focuses on translating peer-reviewed research into formulations that support cellular energy, methylation, and longevity.

Let's dive in.

Use code YOUNGGOOSE at https://www.qualialife.com/ for a special discount.

What's Discussed:

(4:32) Why creatine went from a niche Olympic edge to a billion-dollar category after the 1992 Games.

(11:18) The sloping-surface analogy that explains why 5 grams saturates muscle but barely touches the brain.

(15:47) How creatine buffers cognitive performance under sleep deprivation, with no decrement at baseline.

(22:05) Why the bloating myth is backwards and what intracellular hydration actually feels like.

(28:40) Topical creatine, the dermal layer, and why molecule size matters for skin delivery.

(36:22) The decade of creatine in women: bone density, mood, and energy fluctuations through menopause.

(42:15) Where the hair loss rumor really came from, and why creatine took the blame.

(51:08) Why 40% to 70% of your body's methylation goes to making creatine, and what that means for NAD stacking.

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Dr. Dan Pardi:

Instagram: @drdanpardi

Substack: @drdanpardi

Find more from Qualia:

Website: qualialife.com

Instagram: @qualialife

Qualia Creatine: qualialife.com/shop/qualia-creatine

When summer skin starts looking dull, congested, tired, or slower to recover, it is easy to blame the obvious things: heat, sweat, sunscreen, long days outside, or the wrong moisturizer. So the conversation usually stays on the surface. Use SPF. Cleanse better. Switch to lighter products. Add antioxidants. But before we treat summer skin like another product problem, there is a deeper question worth asking: what is the sun doing to the cell before you ever see the damage in the mirror?

In this episode of Biohacking Beauty, I want to take the sun conversation past burns, wrinkles, and dark spots. I’m walking through what UV exposure does to the systems your skin depends on to keep up with summer: cellular energy, NAD, mitochondrial function, and DNA repair. Because the skin does not only need protection from the sun. It also needs enough repair capacity to deal with the damage that gets through.

Young Goose's Skin Under the Sun campaign is active from June 15 through June 28 at younggoose.com

What’s Discussed:

(01:50) The light-activated repair tool humans lost.

(06:10) Why NAD matters for skin energy and repair.

(10:15) How UV exposure increases oxidative stress and disrupts NAD supply.

(16:44) What UV-induced DNA lesions are and why CPDs matter.

(22:21) Why L.A.D.R. serum was built around light-activated repair-inspired science.

(31:52) Why the sun is one of the biggest controllable inputs into biological skin aging.

(35:43) The five protocol-level moves for supporting skin through summer.

Listen to this episode of Biohacking Beauty to understand what UV is doing under the surface and how to build a smarter summer protocol around protection, energy, and repair.

Resources Mentioned:

Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Every fibroblast inside your dermis right now is asking 200 to 2,000 mitochondria to power its work in real time, and those mitochondria are descendants of a free-living bacterium swallowed by a larger cell 2 billion years ago. As you age, those mitochondria run slower and your cells build fewer of them to replace the ones that fail.

In this solo episode, Young Goose co-founder Amitay Eshel breaks down the two sides of mitochondrial decline that drive skin aging and explains why the science-led skincare category has spent the last decades addressing only one of them.

The first side of skin aging is where most skincare brands have built their products around. The other side is the one almost no skincare on the market is formulating for, and it is where the next chapter of skin longevity is being written.

If you have outgrown the antioxidant-and-peptide era of skincare and want to understand what is actually happening underneath your skin as it ages, this episode is for you.

What's Discussed:

(01:35) The 2-billion-year-old contract inside every skin cell that is now fraying.

(04:10) Why skin is one of the most mitochondria-dense organs in your body.

(08:20) The 2012 paper that showed NAD drops by half between 35 and 70.

(13:15) How a refugee fired in 1933 figured out the chemistry your cream still runs on.

(16:30) The second half of the decline almost no skincare addresses.

(19:45) The master regulator that decides whether your cells can hire.

(24:00) The two columns of mitochondrial biology and why most brands only work in one.

(32:10) Why this is a ten-year strategy, not a two-week one.

Resources Mentioned:

Download the Cellular Energy Protocol: https://www.younggoose.com/pages/the-mitochondrial-skin-stack

Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare