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Biohacking Beauty: The Anti-Aging Skincare Podcast

Biohacking Beauty: The Anti-Aging Skincare Podcast

By: Young Goose
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Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond "single-molecule" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.Copyright 2026 Young Goose Alternative & Complementary Medicine Art Hygiene & Healthy Living
Episodes
  • 275. Dave Asprey: The Uncomfortable Conversation About Aging Naturally vs. Biohacking

    275. Dave Asprey: The Uncomfortable Conversation About Aging Naturally vs. Biohacking
    Oct 14 2026

    There is an interesting contradiction in the way we talk about aging. We celebrate using technology to improve sleep, metabolism, cognition, recovery, and longevity, but when the same mindset is applied to appearance, the conversation can suddenly become much more judgmental.

    In this episode of Biohacking Beauty, we sit down with Dave Asprey to explore that tension. We get into why he chose a facelift after major weight loss, whether cosmetic procedures belong in the biohacking conversation, and why wanting to look younger is often treated differently from wanting the rest of your body to function younger.

    Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, CEO of Upgrade Labs, host of The Human Upgrade, and co-founder of Unlimited Life. We also talk about how he prepares his body before procedures, what he thinks people misunderstand about peptides, and his takes on GLP face, collagen supplements, Botox, stem cells, and the other tools people are using to change how they age.

    What’s Discussed:

    [13:02] Why Dave ultimately chose a facelift after major weight loss.

    [15:24] Where non-surgical skin treatments reached their limit for the amount of excess skin he wanted to address.

    [18:58] Why copying someone else’s longevity or supplement stack can backfire.

    [28:59] Where to start when your biological-age markers look good but you still do not like what you see in the mirror.

    [30:07] Why sleep, recovery, HRV, and other foundational markers still matter when thinking about aging.

    [37:52] The stigma around cosmetic procedures in biohacking and why Dave questions where that line is drawn.

    [44:56] Why he believes fear around aging and medical procedures can affect the body’s stress response.

    [54:25] GLP-1s, muscle loss, and the changes people notice in facial appearance after weight loss.

    Listen to this episode of Biohacking Beauty for a conversation about where “aging naturally” ends, where biohacking begins, and why that line becomes much more complicated when appearance enters the picture.

    Find more from Young Goose:

    Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off atyounggoose.com

    Instagram: @young_goose_skincare

    Find more from Dave Asprey:

    Website:daveasprey.com

    LinkedIn: Asprey

    Instagram:@dave.asprey

    Facebook: Daveaspreyofficial

    YouTube: DaveAspreyBPR

    TikTok: @daveaspreyofficial

    Book: “Heavily Meditated”: https://daveasprey.com/heavily-meditated/
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    48 mins
  • 274. The Peptide Skincare Boom: Separating Skin Science From Marketing

    274. The Peptide Skincare Boom: Separating Skin Science From Marketing
    Oct 7 2026
    Peptides are everywhere in skincare right now. They are in serums, moisturizers, lip products, cleansers, body washes, and even shampoos, all promising some version of smoother skin, more collagen, or fewer visible signs of aging.But seeing “peptides” on a label tells you very little about whether the product can actually deliver those results. Which peptide is being used? Is there research behind that specific ingredient? Is there enough of it in the formula? Can it get through the skin barrier? And what happens when it is combined with everything else inside the bottle? So before you buy another peptide serum because the ingredient sounds impressive, it is worth knowing what actually makes a peptide useful for your skin and how formulation, delivery, concentration, and the rest of your routine can affect whether it works at all.In this Biohacking Beauty Class, we are separating the science from the marketing around topical peptides. We get into which ones have more evidence behind them, what “Botox in a bottle” gets wrong, why some peptide products make more sense than others, and what to look for if your goal is supporting collagen, softening fine lines, and keeping your skin functioning well as it ages.What’s Discussed:(01:47) Do peptides actually belong in everything from serums to body wash?(05:17) The biggest red flag when a skincare product uses peptides as the main selling point.(08:26) What should actually back up an anti-aging peptide claim.(11:11) Which topical peptides have more evidence behind them.(13:01) Why neuropeptides are not really “Botox in a bottle.”(15:54) What to know about using peptide products with vitamin C, retinoids, and other actives.(17:46) Why pH, concentration, and the other ingredients in a formula can affect peptide stability.(21:14) What actually makes a topical peptide product more likely to work.(22:45) Why healthy skin function still matters when you are trying to support collagen and repair.(25:09) If you could only add one peptide product to your routine, which type should it be?Listen to this episode of Biohacking Beauty before another peptide claim on a skincare label convinces you to spend more without knowing what is actually inside the formula.Previous Episodes Mentioned:Nathalie Niddam: Peptides, Bioregulators, and the Truth About Skin Longevityhttps://podcasts.apple.com/us/podcast/nathalie-niddam-peptides-bioregulators-and-the/id1552026927?i=1000736397042Nathalie Niddam: The Potential of Peptides in Skin Health and Anti-Aginghttps://podcasts.apple.com/au/podcast/nathalie-niddam-the-potential-of-peptides-in-skin/id1552026927?i=1000642759851Peptides episodes to watch:Peptides, Bioregulators & The Truth About Skin Longevity | Nathalie Niddam:: https://www.youtube.com/watch?v=2AoqcXJ_MMcWhy Peptides Are Not the Shortcut Biohackers Think They Are with Chris Duffin: https://www.youtube.com/watch?v=UNPhDZXY6kwPeptides, Hormones, and the Anti-Aging Protocol Most Women Start Too Late: https://www.youtube.com/watch?v=b_CTcFjeyqQ&t=428sGHK-Cu Explained: The Copper Peptide That Signals Collagen Repair: https://www.youtube.com/watch?v=qGDNyVtZjl4Find more from Young Goose:Website: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.comInstagram: @young_goose_skincare
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    25 mins
  • 273. Dr. Staci Whitman: The Surprising Oral Causes Behind Facial Asymmetry and How Your Face Ages | Part 2

    273. Dr. Staci Whitman: The Surprising Oral Causes Behind Facial Asymmetry and How Your Face Ages | Part 2
    Sep 30 2026
    You probably know which side of your face you prefer in photos. One jawline may look sharper. One cheek may sit differently. One under-eye may look darker. And while some facial asymmetry is completely normal, the way you use your mouth can also influence how the two sides of your face function over time.In Part 2 of our conversation with Dr. Staci Whitman, we look at facial aging from inside the mouth. We get into how one-sided chewing, bite patterns, tongue function, palate width, airway health, and jaw structure can influence facial symmetry and the way changes become visible in the face. We also explore what adults can realistically do when the issue is structural rather than purely cosmetic. Dr. Staci breaks down the conversations happening around mastic gum, myofunctional therapy, palate expansion, MARPE, oral appliances, and tongue-tie releases, including why changing the way the mouth functions is much more complicated than trying the latest jawline trend online.Dr. Staci Whitman is a board-certified pediatric dentist and Functional Medicine Certified Practitioner whose work focuses on functional dentistry, airway health, craniofacial development, the oral microbiome, and the mouth-body connection. She is the co-founder of the Institute for Functional Dentistry and founder of Bloom + Brighten.What’s Discussed:[1:37] Why persistent dark under-eyes may sometimes point to airway issues, inflammation, and facial structure rather than pigmentation alone.[3:32] What happens to the jaw and the bones supporting the face as we age.[6:44] How chewing predominantly on one side may contribute to differences between the two sides of the face.[10:55] What your chewing patterns, saliva, and cavities may reveal about how you are using your mouth.[17:09] Whether mastic gum and jaw exercises can actually change the appearance of an adult face.[20:00] How tongue function, swallowing, and breathing are addressed through myofunctional therapy.[21:50] Why a narrow palate may require more than simply changing your tongue position.[22:30] What adults should know about palate expansion, MARPE, and oral appliances.[31:26] Why finding a tongue tie does not automatically mean releasing it is the first step.[40:49] Who to see when you suspect your bite, tongue, airway, or jaw function may be affecting your face.Listen to this episode of Biohacking Beauty to learn why facial asymmetry may be giving you clues about what is happening inside your mouth. Find more from Young Goose:Website: www.younggoose.com/Use code PODCAST10 to get 10% OFF your first purchase, and if you are a returning customer use code PODCAST5 to get 5% OFF.Instagram: @young_goose_skincareFind more from Dr. Staci Whitman:Website: doctorstaci.comInstagram: @doctor_staciTikTok: @doctor_staciYouTube: youtube.com/channel/Book: SPIT: Why Your Mouth-and Its Microbes-Are the Secret to Whole-Body, Lifelong HealthRead Dr. Staci’s newsletter: substack.com/@doctorstaci ResourcesFind an oral-systemic health practitioner through AAOSH: aaosh.org/find-a-practitionerSearch the IAOMT directory for a biological dentist or health professional: iaomt.org/for-patients/Search/?ppage=dashboardFind an airway-focused practitioner through AAPMD: aapmd.org/find-aapmd-professionalSearch The Breathe Institute provider directory: breatheops.com/directory/the-breathe-instituteLearn more about the Institute for Functional Dentistry: functionaldentistry.org/
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    46 mins
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