Homer Wells' odyssey begins among the apple orchards of rural Maine. As the oldest unadopted child at St Cloud's orphanage, he strikes up a profound and unusual friendship with Wilbur Larch, the orphanage's founder - a man of rare compassion and an addiction to ether. What he learns from Wilbur takes him from his early apprenticeship in the orphanage surgery, to an adult life running a cider-making factory and a strange relationship with the wife of his closest friend.

Of all of John Irving's books, this is the one that lends itself best to audio. In print, Owen Meany's dialogue is set in capital letters; for this production, Irving himself selected Joe Barrett to deliver Meany's difficult voice as intended. In the summer of 1953, two 11-year-old boys – best friends – are playing in a Little League baseball game in Gravesend, New Hampshire. One of the boys hits a foul ball that kills the other boy's mother. The boy who hits the ball doesn't believe in accidents; Owen Meany believes he is God's instrument. What happens to Owen after that 1953 foul ball is extraordinary and terrifying.

Born a Parsi in Bombay, sent to university and medical school in Vienna, Dr. Farrokh Daruwalla is a 59-year-old orthopedic surgeon and a Canadian citizen who lives in Toronto. Once, 20 years ago, Dr. Daruwalla was the examining physician of two murder victims in Goa, India. Now, 20 years later, he will be reacquainted with the murderer.

As we grow older - most of all, in what we remember and what we dream - we live in the past. Sometimes we live more vividly in the past than in the present. As an older man, Juan Diego will take a trip to the Philippines, but his dreams and memories will travel with him; he is most alive in his childhood and early adolescence in Mexico. 'An aura of fate had marked him,' John Irving writes.

A compelling novel of desire, secrecy, and sexual identity, In One Person is a story of unfulfilled love - tormented, funny, and affecting - and an impassioned embrace of our sexual differences. Billy, the bisexual narrator and main character of the novel, tells the tragicomic story (lasting more than half a century) of his life as a "sexual suspect," a phrase first used by John Irving in 1978 in his landmark novel of "terminal cases", The World According to Garp.

The postcard has been held at the sorting office for 91 years, waiting to be delivered to Joe Tournier. On the front is a lighthouse - Eilean Mor, in the Outer Hebrides. Joe has never left England, never even left London. He is a British slave, one of thousands throughout the French Empire. He has a job, a wife, a baby daughter. But he also has flashes of a life he cannot remember and of a world that never existed - a world where English is spoken in England and not French.

Victor Alderheim has a lot to answer for. Not only has he heartlessly tricked his young ex-wife, Jenny, out of her art gallery inheritance, but he has also abandoned his son, Kevin, to die in the middle of the Kenyan savanna. It doesn’t occur to Victor that Kevin might be rescued and adopted by a Maasai medicine man, or that he might be expected to undergo the rituals expected of all new Maasai warriors - which have him running back to Stockholm as fast as you can say circumcision without anaesthetic.

Émile Zola's The Kill is one part of the French author's 20-volume series about the fictitious Rougon-Macquart family during the Second French Empire, and it is rich with symbolism. Paris is awakening to unprecedented expansion, the future intoxicating, and in keeping with its penchant for excess, the aristocracy is caught up in the mad dash to devour as much of it as it can.

Starting in 1758, a young Matthieu flees Paris after witnessing his mother's brutal murder. His only companions are his younger brother, Tomas, and one true love, Dominique Sauvet. The story of his life takes us from the French Revolution to 1920s Hollywood, from the Great Exhibition to the Wall Street Crash - and by the end of the 20th century, Matthieu has been an engineer, a rogue, a movie mogul, a soldier, a financier, a lover to many, a cable TV executive and much more besides.

From her place in the store, Klara, an Artificial Friend with outstanding observational qualities, watches carefully the behaviour of those who come in to browse and of those who pass in the street outside. She remains hopeful a customer will soon choose her, but when the possibility emerges that her circumstances may change for ever, Klara is warned not to invest too much in the promises of humans.

Things have never been easy for Oscar. A ghetto nerd living with his Dominican family in New Jersey, he's sweet but disastrously overweight. He dreams of becoming the next J R R Tolkien and he keeps falling hopelessly in love. Poor Oscar may never get what he wants, thanks to the Fuku - the curse that has haunted his family for generations.

A woman known for her viral social media posts travels the world speaking to her adoring fans, her entire existence overwhelmed by the internet - or what she terms ‘the portal’. Are we in hell? the people of the portal ask themselves. Are we all just going to keep doing this until we die? Suddenly, two texts from her mother pierce the fray: "Something has gone wrong", and "How soon can you get here?" 

It's 1959, and Harry 'Rabbit' Angstrom, one-time high school sports superstar, is going nowhere. At twenty-six he is trapped in a second-rate existence - stuck with a fragile, alcoholic wife, a house full of overflowing ashtrays and discarded glasses, a young son and a futile job. With no way to fix things, he resolves to flee from his family and his home in Pennsylvania, beginning a thousand-mile journey that he hopes will free him from his mediocre life.

Hans Castorp is, on the face of it, an ordinary man in his early 20s, on course to start a career in ship engineering in his home town of Hamburg, when he decides to travel to the Berghof Santatorium in Davos. The year is 1912 and an oblivious world is on the brink of war. Castorp’s friend Joachim Ziemssen is taking the cure and a three-week visit seems a perfect break before work begins. But when Castorp arrives he is surprised to find an established community of patients, and little by little, he gets drawn into the closeted life and the individual personalities of the residents.

It is 1981. Glasgow is dying and good families must grift to survive. Agnes Bain has always expected more from life. She dreams of greater things: a house with its own front door and a life bought and paid for outright (like her perfect, but false, teeth). But Agnes is abandoned by her philandering husband, and soon she and her three children find themselves trapped in a decimated mining town. As she descends deeper into drink, the children try their best to save her, yet one by one they must abandon her to save themselves. It is her son Shuggie who holds out hope the longest.