Along a blacked-out wartime street a girl is scurrying, a basket on one arm. As sirens begin and bombs crash down, she is filled with panic and, with a heavy heart, abandons her burden in a sheltered doorway, meaning to return later. Even as she disappears in the resulting chaos, the bundle in the basket begins to wail.

Claudia Muldoon and her sister, Jenny, live with their parents and their gran in her house in Blodwen Street. Both parents have good jobs and the family assume they are settled for life, but then Grandpa Muldoon has a seizure and begs his son to return to Ireland. In Ireland the Muldoons flourish and the girls love the freedom of their new life, though as they grow up, disadvantages become clear. Claudia has to find work, so both sisters return to Liverpool and to their old pal Danny, who welcomes them back with delight.

It's 1938, and Cadi is chosen to be Rose Queen in the annual Rose Fete. She is thrilled to be treated like royalty for the day. But deep down she is desperate to leave the Welsh mining community where she grew up. When war is declared, Cadi and her best friend, Poppy, see a chance to escape. Cadi leaves behind her parents and local boy Aled, whom she is meant to marry, for Liverpool.

Marianne seems to have everything. She is married to a handsome Naval officer, Neil Sheridan. They have a daughter, Libby, and a beautiful home near Prince's Park in Liverpool. When war comes, Marianne takes war work and moves in with her mother, Mrs Wainwright, and younger sister. Neil disapproves because the Wainwrights live close to the docks, which are bound to be a bombing target, but Marianne is firm.

Miranda Lovage and her mother have a blazing row when Arabella tells her daughter that she can no longer afford their present lifestyle. Miranda goes to bed angry and upset. When she awakes next morning, however, it is to find that her mother has disappeared. Miranda raises the alarm but everyone is baffled, and when searches fail to discover Arabella's whereabouts, Miranda is forced to live with her Aunt Vi and cousin Beth, who resent her presence and treat her badly.

Liverpool, 1934. Hester Lowe agrees to act as governess to spoiled, self-willed little Lonnie Hetherington-Smith when they leave India to live with Lonnie’s elderly aunt in Shaw Street, Liverpool. Hester speedily realises that her new employer dislikes her niece and means to make life uncomfortable for both of them. Things improve a little when they meet the poor but happy Bailey family, who live in a court off Heyworth Street. Hester likes Dick Bailey very much, but her employer does not permit 'followers', and Lonnie and young Ben Bailey are deadly enemies. 

Laura Collins is struggling to make a good life for her daughters, Tess and Tina. So when she is offered a good job, with accommodation, she is delighted. Life is very different for the Brewsters who live on Manor Farm in Herefordshire. Danny plans to marry one day so that he can take over the farm, whilst his cousin, Phil, longs to escape the world of farming as soon as possible. War changes all their plans.

1901. Tina Rose is the beloved daughter of a wealthy Jewish family while Edward grew up with an abusive father in the wilds of New Zealand. Despite their differences, the two fall madly in love when Edward arrives in England, looking for a better future. However, the consequences of their love affair are terrible for Tina, as she is shamed by the father she adores, and Edward is sent away. Against all the odds, Tina and Edward find each other again.

Jess and Nancy, nursing in France during the Great War, are very different girls with much in common. Both have lost their lovers in the trenches, so when the war is over, they return to a bleak future, nursing in Liverpool. Very soon, however, their paths diverge. Nancy marries an Australian and goes to live in the Outback whilst Jess marries a Liverpudlian. Both have children; Nancy's eldest is Pete, and Jess has a daughter, Debbie. 

Nell Whitaker is 15 when war breaks out and her mother sends her to live with her Auntie Kath in a remote farmhouse on Anglesey. At first Nell hates it, but her friendship with Bryn, who works on the farm whilst waiting for his call-up papers, helps a lot. So when he leaves to join his ship, Nell is counting the days to his return. But her heart is broken when news reaches her that Bryn’s ship has been bombed and he has been drowned. Determined to bury her grief in hard work, Nell finds herself growing closer to Auntie Kath.

Addy and Prue Fairweather live with their widowed mother Nell, in a flat above her shop. Addy is plain and always in trouble whereas Prue is as angelic as her looks imply. To make matters worse, Nell makes no secret of her preference for the younger girl, increasing Addy's jealousy. On the other side of the coin, Giles Frobisher and his twin sister, Gillian, live in a crumbling mansion in Devon. The family have lost most of their money in the Depression, so Giles joins the Fleet Air Arm.

Lottie and her mother, Louella, share a house in Victoria Court with Mr Magic and his son, Baz. Lottie is a child star, dancing and singing at the Gaiety Theatre; Louella acts as Max Magic's assistant. But a road accident causes Lottie to lose her memory. Then Lottie meets a boy with golden-brown eyes who calls her "Sassy" and accuses her of running away. It is after this meeting that the dreams start, dreams of another life, almost another world.

It is the autumn of 1945 and identical twins Joy and Gillian Lawrence are on their way home to Liverpool, having been evacuated to Devonshire five years earlier. Their mother has been killed in the blitz but the girls hope that with their beloved father’s help they will be able to manage. All goes well until there is a terrible accident and Joy loses her sight. At first she is bitter and resentful whilst Gillian is racked with guilt.

Imogen, Rita and Debby all missed the original evacuation and now the authorities are finding it difficult to place them. When Auntie and her niece, Jill, who run the Canary and Linnet Public House, offer to take them in, the billeting officer is greatly relieved. The countryside is heaven to the three little townies, especially after they meet Woody and Josh. They find that by climbing to the top of a tree they are able to watch the comings and goings of the young fighter pilots.

Amy Logan’s family are poor but proud. They scrape a living by shrimping for the big Liverpool fish market, which Amy hates. It’s only because her beloved - and strict - mother rules her with a rod of iron that she mucks in. But Isobel Logan dies in childbirth, and Amy and her brothers start to run wild. Matters aren’t helped when her father marries Suzie Keagan from down the street. Until now, Suzie has managed to conceal a dislike for housekeeping, and she forces Amy to slave at chores. Desperate to escape, Amy leaves home to take her first job.