It's 1965 and Annie Peters is just eight years old when her mother is committed full time to a mental health organization. Uprooted by their mother's illness, Annie and her 4 siblings find themselves torn between a Catholic-run orphanage and the final remnants of their shattered home. As tumultuous church and state changes begin to collide with the lure of an escalating pop culture movement, the orphans of St. Vincents are determined to maintain the fierce independence that would forever mark America's early baby boomer generation.