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Lifespan

Why We Age - and Why We Don’t Have To
Narrated by: Dr David A. Sinclair
Length: 11 hrs and 55 mins
4.7 out of 5 stars (705 ratings)

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Summary

In this paradigm-shifting audiobook from acclaimed Harvard Medical School doctor and one of Time magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically proven methods that can help listeners live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no-one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable.

But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable.

In Lifespan, Dr David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this audiobook, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit.

This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome - has enabled earth’s early microcosms to survive and evolve into more advanced organisms.

But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes.

Drawing on his cutting-edge findings at the forefront of medical research, Dr Sinclair will provide a scientifically proven road map to reverse the genetic clock by activating our vitality genes, so we can live younger longer.

Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes.

Dr Sinclair ends the audiobook with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more.

Dr Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. Lifespan is destined to be the biggest book on genes, biology, and longevity of this decade.

PLEASE NOTE: When you purchase this title, the accompanying reference material will be available in your Library section along with the audio on our desktop site.

©2019 Dr David A. Sinclair (P)2019 HarperCollins Publishers Limited

Critic reviews

"If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant." (Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and number one New York Times best-selling author)

"This is the most visionary book about aging I have ever read. Seize the day - and seize this book!" (Dean Ornish, MD, founder and president, Preventive Medicine Research Institute, and New York Times best-selling author of UnDo It!

What listeners say about Lifespan

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    3 out of 5 stars

Good science bundled with annoying social justice

The book starts well, with a bit of biographical information that informs us why he is trying to help people live longer, and goes into some excellent science on the topic. I was fascinated by the history of his research into his own theory of ageing, how his and other theories have played out over time, and the current state of play. Unfortunately the final section is pure social theory, unsupported left wing talking points and climate alarmism presented as fact. Honestly when he makes statements about how he is proud he is of his son, who wants to become a social justice activist and politician, and that the world needs people like him to break the "global patriarchy" - then goes on to wonder at why his son is depressed and doesnt value his work to increase lifespan... well.... lets just say I'm suddenly re-evaluating everything else Sinclair says. I'll take his expertise on the science of ageing, but I think I'll pass on the rest. Damn shame, if he had spent the time focusing on the science, rather than pushing a social agenda or placing arguments down only for a specific demographic, the book could have been great.

20 people found this helpful

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only two takeaways and allot of story telling

so to save time, restricting eating or intermittent fasting and take mnm and resveratrol. done your most welcome. book started well with an impacting intro but in the end especially towards the end of the book I had to speed it up to get to anything of note and at the end it was mostly about the writers visions and sales to government to give more funding.

21 people found this helpful

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This book will change your life and the world.

A lot of people are going to talk about the book. Get in ahead of the curve and read/listen to it now. In David's own words this book will be out of date in 2/3 years because the science of longevity is evolvibg all the time. Which is a good thing. And I hope is get some revisions in a couple or years. David has also taken the time to speak the book himself which is very time consuming and he should also receive merit for that too. This book is amazing and definitely worth a listen. I really hope a lot of people from governments and health organisations get to read/listen to it and talk about it. If this book doesn't change the world David Sinclair definitely will. It's science fiction coming true again just like self driving cars and free energy is also coming true. I heard about the book from Dave Asprey and Dr Joe Mercola who's books are also worth a read/listen.

4 people found this helpful

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Fantastic

great book, if you are interested in longevity and the science behind it, read this!

2 people found this helpful

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Informative

The information given on ageing and disease is invaluable. The stories were a bonus.

2 people found this helpful

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Heady aspirations.

Life extension research and it's implications. Personally I enjoyed the science parts at the beginning of the book. The implications of longer lives felt like it was turning into a sermon and went on too long for me. On the whole exciting science though and Dr Sinclair definitely has the enthusiastic voice & experience to rally the charge.

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Some interesting information

I read the book from cover to cover. I think the information he provides needs to be taken with a grain of salt, not the one about the possibility of expanding or lifespan funny enough. I actually liked DR David Sinclair before reading the book but at a certain point I felt a major brainwash coming and I was right, when he started talking about how safe GMO’s are and how amazing Bill Gates is he completely lost me. I understand to live naturally is hard or even impossible, but we all know the doggy things in studies published about GMO and withdrawn after heavy lobbying from GMO companies, or do we? Funny enough even the University he is representing has fallen in my eyes, it makes sense now what sort of games they are playing and as always... money talks!

1 person found this helpful

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Not especially to the point

I expected a learning resource from this. Instead, this is filled with little anecdotes about the authors life as well as countless name drops. I don't especially care for someone's rather boring academic life story. The entire book could have spanned a single chapter, or maybe he should have stuck with writing journal entries.

1 person found this helpful

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Sound science

Really enjoyed the audiobook. David Sinclair is brilliant and opinionated. He is an authority in the science of aging, and can teach you what works to live longer and what is to come. Social/political issues discussed in the last section of the book may be a bit biased, but the discussion still was reasonable and relevant.

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Mind blowing

I loved it - a complete paradigm shit that may add decades of healthy life to your lifespan.

1 person found this helpful

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  • Jim
  • 07-01-20

Will change your life, if you let it.

A book that so many around the world should read, if only a small amount of what is in this book it's taken on by everyone around the world it will be a big step forward. Great insights and food for thought.

1 person found this helpful

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  • Robert Tessier
  • 26-12-19

David Sinclair is one of the great human been

Thanks David to change the world the way you do. This book should be teach to all student at school.

1 person found this helpful

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  • beinloveart
  • 20-12-19

Buy the paperback for all the people you love

It’s a beautiful book to listen to; and I can see that David Sinclair will be written in the history books as the man who fought to convert 21st century medicine scholars into focusing on ageing as a disease, rather than wasting so much of each countries taxed funds on individual diseases. He makes me so proud to be an Australian. Thanks David and family.

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  • Amazon Customer
  • 12-11-19

Excellent! Loved the listen.

I would highly recommend this this audio book. I really enjoyed listening to all the latest research and understanding why things work the way they do. This book could potentially have a major impact on your life.

1 person found this helpful

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  • Robert H
  • 28-10-19

Mind Altering Book

One of the most life changing ( if I can use this expression) books I have ever read. The warmth & deep sincerity of David Sinclair ( I used the audio book) resonates deeply.

1 person found this helpful

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  • Mario Tomic, MSc
  • 10-09-19

Must-Read If You're Interesting in Healthy Aging

Coming from a perspective of someone who studies evidence-based nutrition, exercise, and healthy lifestyle factors for over a decade now, this book is a must-read. Solving aging is one of the final frontiers for humankind, and the information David has provided here is a big step in the right direction. It has the power to bring more awareness to solving aging as well as shift strong limiting beliefs that have been deeply rooted in public as well as the scientific community. We've come very far in research, but sadly the mainstream still hasn't caught up as many of the theories often mentioned have already been invalidated. Big thanks to David and his team for putting together all the most up-to-date longevity research in one place.

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  • Setken
  • 26-08-20

Human longevity science made understandable

Dr. Sinclair discsses his research and successes with longevity science, and is not afraid to give his personal opinions on the subject either - rare for scientists usually. It is in fact this human-ness that gives the book its charm, and likely why he'll be successful in sorting aging out once and for all. I believe that good people with good intentions ultimately reach their aims. I am hoping and praying that he does, for all of us.

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  • Heetendra
  • 10-08-20

Now that's a postive book!!

This is a book you will not regret reading. Well worth it! Needs multiple reads. momo

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  • Anonymous User
  • 18-02-20

Best book on Longevity

Great book about achievements of longevity studies and positive perspective. Lots of great information. And David is simply amazing.

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  • Anonymous User
  • 18-02-20

Insightful and useful read

Must read for anyone keen to learn and apply a little more to their well being. The cutting edge information on how to optimise your health is invaluable! Can't thank Dr Sinclair enough for his efforts and generosity for sharing information.