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Lifespan

Why We Age - and Why We Don’t Have To
Narrated by: Dr David A. Sinclair
Length: 11 hrs and 55 mins
5 out of 5 stars (95 ratings)

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Summary

In this paradigm-shifting audiobook from acclaimed Harvard Medical School doctor and one of Time magazine’s 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically proven methods that can help listeners live younger, longer.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no-one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable.

But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable.

In Lifespan, Dr David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that. He has dedicated his life’s work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this audiobook, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit.

This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome - has enabled earth’s early microcosms to survive and evolve into more advanced organisms.

But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.

But genes aren’t our destiny; we have more control over them than we’ve been taught to believe. We can’t change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes.

Drawing on his cutting-edge findings at the forefront of medical research, Dr Sinclair will provide a scientifically proven road map to reverse the genetic clock by activating our vitality genes, so we can live younger longer.

Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes.

Dr Sinclair ends the audiobook with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more.

Dr Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. Lifespan is destined to be the biggest book on genes, biology, and longevity of this decade.

PLEASE NOTE: When you purchase this title, the accompanying reference material will be available in your Library section along with the audio on our desktop site.

©2019 Dr David A. Sinclair (P)2019 HarperCollins Publishers Limited

Critic reviews

"If you ever wondered how we age, if we can slow or even reverse aging, and if we can live a healthy 100 plus years, then David Sinclair’s new book Lifespan, which reads like a detective novel, will guide you through the science and the practical strategies to make your health span equal your lifespan, and make your lifespan long and vibrant." (Mark Hyman, MD Director, Cleveland Clinic Center for Functional Medicine and number one New York Times best-selling author)

"This is the most visionary book about aging I have ever read. Seize the day - and seize this book!" (Dean Ornish, MD, founder and president, Preventive Medicine Research Institute, and New York Times best-selling author of UnDo It!

What members say

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This book will change your life and the world.

A lot of people are going to talk about the book. Get in ahead of the curve and read/listen to it now.

In David's own words this book will be out of date in 2/3 years because the science of longevity is evolvibg all the time. Which is a good thing. And I hope is get some revisions in a couple or years.

David has also taken the time to speak the book himself which is very time consuming and he should also receive merit for that too.

This book is amazing and definitely worth a listen.

I really hope a lot of people from governments and health organisations get to read/listen to it and talk about it. If this book doesn't change the world David Sinclair definitely will. It's science fiction coming true again just like self driving cars and free energy is also coming true.

I heard about the book from Dave Asprey and Dr Joe Mercola who's books are also worth a read/listen.

2 of 2 people found this review helpful

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important book to listen

Though the research and the information on it it is incredibly interesting and very important for everybody over the age of 40, there is a big chance of a book that is just maybe not that important. general ideas on ageing, population growth and such, could have been much shorter. I would definitely like to listen to the parts 3 and also to the last three chapters of book. this science part is a little bit difficult for non-scientists, but listen to it and maybe repeat, and you will grasp.

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A must read

beautifully laid sometimes hard to follow due his technical nature. definitely has to be read multiple times

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Life never be the same

Must read it, if you want to understand the direction of the future, get practical knowledge on health, be aware of yourself.
Life changing book!

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Fascinating from start to finish

Seems like something out of science fiction, easy for average people like myself to follow but very complete and detailed too.

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An informative and thought provoking read.

An interesting, informative and thought provoking read. Thoroughly enjoyed it and the insight into the most recent research on anti ageing

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Cutting Edge Science

I hope this book goes on to change people's attitudes towards aging. I like the idea of being able to get older and wiser, yet my body and mind having more time to make use of that wisdom. Dr Sinclair is the herald.

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AWESOME!

This book is a must read and a game changer! Our future is very exciting...

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The author just waffles on

If you are looking for information to find how to increase your lifespan, you've come to the right place. I was a bit let down by the author's waffling on over opinions, and feel it was too much of a let down with regards to liberal opinion, bordering on SJW and pushing the vegan agenda. I had to return the book unfortunately.

0 of 1 people found this review helpful

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Brilliant

Great read very interesting to see what the future might hold for us with the stuff they are working on fully recommend

0 of 1 people found this review helpful

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  • Mario Tomic, MSc
  • 10-09-19

Must-Read If You're Interesting in Healthy Aging

Coming from a perspective of someone who studies evidence-based nutrition, exercise, and healthy lifestyle factors for over a decade now, this book is a must-read. Solving aging is one of the final frontiers for humankind, and the information David has provided here is a big step in the right direction. It has the power to bring more awareness to solving aging as well as shift strong limiting beliefs that have been deeply rooted in public as well as the scientific community. We've come very far in research, but sadly the mainstream still hasn't caught up as many of the theories often mentioned have already been invalidated. Big thanks to David and his team for putting together all the most up-to-date longevity research in one place.

1 of 1 people found this review helpful

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  • CMWalke
  • 28-09-19

Essential Reading

That we will find ways to extend healthy human lifespans is no longer really in doubt. How fast we manage to beat the most pernicious of all diseases is really the key... to keeping our parents and grandparents around. The socioeconomic work we need to does a civilisation is even more important. David makes an excellent set of points eloquently and with real humanity. We’re lucky to have him at this point in history. ...now to find a source of excellent quality nmn for the same price as my resveratrol per gram...

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  • Yoav
  • 26-09-19

Informative and eye opening.

excellent book! comprehensive, fascinating, up to date information. begins with the science, but than sidetracks a lot to discuss philosophy and ethics (a bit too much).

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  • andrew
  • 18-09-19

Science for the ages

A very good book read by the author, none the less. It starts with a compelling personal anecdote and continues with well explained and defined issues, current scientific knowledge, possible solutions, and even looks at the possible downsides. I appreciate most his honesty in his answers, and I like his arguments and logic. There is just enough science to not turn people away but also enough to explain the ideas within the scope of real science terminology. There's also a nice PDF available with the audio book. (the PDF is available in your computer library, i. e. at Audible website accessed via your computer. It's not very clear where PDF is once you're in the mobile app because it's not visible there and the info about how to get it is on the website when you browse)
I came across David Sinclair on Joe Rogan"s YouTube channel. (There's a new one now accompanying the release of this book. ) I never heard of him before but the topic seemed interesting for me to try the 15min video. I liked the way he spoke (its a good way to see if you might like his narration of his own book) his arguments, and I was interested in the science. I goggled him and he had a book coming up (this book). So I marked my calendar and waited 😊. I'm not disappointed. I would recommend this book for anyone.

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  • Amazon Customer
  • 21-09-19

A brilliant scientist, a lousy politician.

it seems like the author couldn't decide whether he wanted to write a scientific book or a political one, so he wrote both. First part is absolutely brilliant, eye opening and has a lot of meat on its bones even for those who reads literature on longevity. Spectacular work. Second part is a leftist bingo. Get ready to hear a lot about climate change, social justice, governmental programs, wealth redistribution and other stuff you can hear by watching CNN. Completely unnecessary and unwanted in a science book.

0 of 1 people found this review helpful