Liverpool 1939: Olivia Campbell appears to have the perfect life. However, behind closed doors she lives in constant fear of her abusive father and has no support from her mother. Longing for love and affection, she begins a relationship with Ted, a young lad who works in her father's factory. But her family disapprove of the relationship and forbid them from seeing each other.

In 1820, Salem Street is sparkling and new: eight small terraced houses built by a Lancashire mill owner for his best workers. Annie Gibson's family is one of the first to move in - a step up in the world for them. But when her mother dies, Annie's happy childhood ends and she is left to bring up her brother and sister. Red-haired, intelligent and startlingly pretty, Annie soon finds herself banished from home by a jealous stepmother. She finds work in the local doctor's household, where she learns about the fascinating world outside Salem Street.

Liverpool, 1940. When war comes to Britain, Jessica Wilson and her friend Ruby seize the opportunity to leave behind the orphanage they grew up in and start new lives in the NAAFI. With only forged papers as identification, the girls expect to be turned away but are delighted with an offer of work. For the first time in their lives they experience real independence, and it isn't long before they're spending their evenings enjoying the delights of Liverpool.

It is 1937, and Alice, Edith and Marg continue to face hardships every day, growing up on one of the poorest streets in Blackpool. Penniless, their friendship has helped them survive this far, but it'll take more than that to see them through the dark days ahead. Alice is coping with a violent father. Marg is left reeling after a dark secret about her birth comes to light and threatens to destroy the life she knows, and Edith is fighting to protect her alcoholic mother from the shame of their neighbours and keep her brother on the straight and narrow. 

A few days before Christmas Tess Williams rushes into Albert Payne's tobacconist shop, with two boys in hot pursuit, saying she's a thief. Albert chases the boys away, and though Tess does not realise it, this incident changes her life. Tess lives with her grandmother, Edie, in a small flat on Heyworth Street. She has recently returned from Bell Farm, where she was evacuated during the war. When the handsome Snowy White comes to her rescue she thinks her troubles are over, and returns to Bell Farm for a working holiday.

Marianne seems to have everything. She is married to a handsome Naval officer, Neil Sheridan. They have a daughter, Libby, and a beautiful home near Prince's Park in Liverpool. When war comes, Marianne takes war work and moves in with her mother, Mrs Wainwright, and younger sister. Neil disapproves because the Wainwrights live close to the docks, which are bound to be a bombing target, but Marianne is firm.

It is the autumn of 1945 and identical twins Joy and Gillian Lawrence are on their way home to Liverpool, having been evacuated to Devonshire five years earlier. Their mother has been killed in the blitz but the girls hope that with their beloved father’s help they will be able to manage. All goes well until there is a terrible accident and Joy loses her sight. At first she is bitter and resentful whilst Gillian is racked with guilt.

Claudia Muldoon and her sister, Jenny, live with their parents and their gran in her house in Blodwen Street. Both parents have good jobs and the family assume they are settled for life, but then Grandpa Muldoon has a seizure and begs his son to return to Ireland. In Ireland the Muldoons flourish and the girls love the freedom of their new life, though as they grow up, disadvantages become clear. Claudia has to find work, so both sisters return to Liverpool and to their old pal Danny, who welcomes them back with delight.

As the worst storm of the century breaks across the Northwest, sweeping through Snowdonia and across the Mersey to burst upon Liverpool, two women, Molly and Ellen, give birth to girls in a Liverpool maternity hospital. Molly lives on a hill farm in Snowdonia while Ellen is married to Sam O'Mara, a dock worker who is quicker with a punch than a kiss. After one punch too many, Ellen throws her husband out and eventually leaves Liverpool to live with Molly. Ellen and her daughter throw themselves into their new life with enthusiasm, unaware that they are being watched by someone hiding in a ruined cottage.

1850. When Opal Sharp finds herself and her younger siblings suddenly orphaned and destitute, she thinks things can get no worse. But soon three of them - including Opal - are struck down with the illness that took their father from them, and her brother Charlie is forced to make an impossible decision. Unable to afford a doctor, he knows the younger children will not survive. So, unbeknownst to Opal, Charlie takes their younger siblings to the workhouse, where he knows they will at least be fed and have a roof over their heads. Opal is heartbroken and struggles to forgive him. 

Liverpool, 1939. As winter descends on Tuppenny Corner and rumours of war float across the canals, 15-year-old Rosie O’Leary must come to terms with her own dramatic upheaval. Forced to say good-bye to all she holds dear and embark on a new life aboard The Kingfisher, her world is suddenly full of uncertainty. But new beginnings open up new possibilities.... When fellow bargee Tim Bradley offers to show Rosie the sights of Liverpool, she jumps at the chance, and it’s not long before their friendship grows into something more. 

Liverpool, 1936. Molly Penelope Hardwick has been abandoned in Haisborough Orphanage. Desperate to discover her background, she befriends another orphan, Lenny Smith. Together they sneak out to roam the city of Liverpool, and hatch plans for their escape. But when Molly is forced to leave the orphanage, Lenny has no idea where she’s gone. And when war is declared, he soon forgets about his childhood best pal to focus on his posting with the RAF in Scrimpton.

Laura Collins is struggling to make a good life for her daughters, Tess and Tina. So when she is offered a good job, with accommodation, she is delighted. Life is very different for the Brewsters who live on Manor Farm in Herefordshire. Danny plans to marry one day so that he can take over the farm, whilst his cousin, Phil, longs to escape the world of farming as soon as possible. War changes all their plans.

Maddy lives with her grandmother in a tumbledown farmhouse in the Yorkshire Dales. The house has been in the family for generations, but her grandmother is struggling to cope. She is determined that no matter what happens, the two of them will not be forced into the workhouse. Though life is tough, Maddy manages to gain a scholarship to the local school. As war is declared, Maddy and her friends join up, leaving the beautiful Dales for the dangerous work of manning the Ack Ack sites.

Miranda Lovage and her mother have a blazing row when Arabella tells her daughter that she can no longer afford their present lifestyle. Miranda goes to bed angry and upset. When she awakes next morning, however, it is to find that her mother has disappeared. Miranda raises the alarm but everyone is baffled, and when searches fail to discover Arabella's whereabouts, Miranda is forced to live with her Aunt Vi and cousin Beth, who resent her presence and treat her badly.