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Epigenetics: How Environment Changes Your Biology

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Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Epigenetics has led to surprises galore, among them that our environment and behavior affects the way our genes work. What’s more, epigenetic research shows that our parents’ environment and behavior also affect our genes, upending the traditional argument on nature versus nurture.

Taught by noted epigeneticist, physician, and science communicator Dr. Charlotte Mykura, Epigenetics: How Environment Changes Your Biology covers the nuts and bolts of this fascinating science in 12 in-depth, half-hour lectures.

Lively and authoritative, Dr. Mykura explains how epigenetics is ubiquitous at the cellular level, influenced by activities like diet and lifestyle. For example, aging is largely an epigenetic phenomenon. So is our susceptibility to many diseases, as well as our body’s ability to fight infection. You learn how epigenetics governs human X and Y chromosomes, the miraculous process of building an embryo, and the transmission of environmental experience between generations. And you investigate how epigenetics evolved in the first place and where the epigenetic universe might take us next, especially in the realm of medicine.

Research in epigenetics has been recognized with several Nobel prizes, and the field will only grow in importance as scientists probe the mystery at the heart of our DNA.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2023 The Great Courses (P)2023 The Teaching Company, LLC
Biological Sciences Evolution & Genetics Genetics Science
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A good introductory level series of lectures on epigenetics. Very interesting, however, the sex genetic section begins heavily weighted towards there being many human sexes. This is not true, although this is so amongst other plant and animal species. This is not substantiated or elaborated on during subsequent discussion, only a genetic fault on the X chromosome in XX embryonic development resulting in development of some male characteristics in extremely rare cases. The lecturer does not refer to this as a rare chromosome disorder which it is. The lecturer rightly does refer to other rare genetic disorders and uses the word disorder. There seems to be a strong bias towards gender ideology at the beginning of this chapter which helps no one suffering from gender dysphoria which is a psychological condition.
Other than the aforementioned chapter, I found the lectures were of a good standard pitched at the layman who may have some pre-existing background knowledge on the subject.
Technically, the narrator stumbles a few times over her words. This should have been sorted out in the editing stage.

Interesting and informative with some limitations

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This book offers a fascinating insight into the theme of epigenetics . Too technical for my original purpose but I kept listening as the narration was excellent and oozing with excitement for the topic.
I had to re-listen some parts due to the many scientific gaps in my knowledge of microbiology, so that was a little annoying, yet educational.

Fascinating

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This book feels as though we are being read a bedtime story, with the theatrical tone and unnecessary pauses. I stopped after chapter 2

If you can get over the “once upon a time” tone

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Refers frequently and sometimes crucially to video material that isn't included. Despite that, it's a great course. Generally recommended, but you have to accept you will need to ignore a bunch of video references.

Not an audiobook

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Charlotte delivers the story of our epigenetics and the ways in which our environment affects our body with vigour and confidence. Although not a biologist, I took a lot away from the key messages of the book.

An accessible and interesting read

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