As artificial intelligence becomes the dominant interface for work, creativity, and competition, some people are adapting to it far faster than others.

In this episode of Endgame, Amanda Cassatt sits down with Dragonfly Capital’s Haseeb Qureshi to explore a generational shift in technological advantage: the biggest winners of every major tech transition are not the most experienced, but the most “pluripotent.”

Younger people, who haven’t yet locked themselves into fixed professional identities, are better positioned to experiment and use new tools as leverage.Haseeb explains how AI intensifies this dynamic.

The key emerging skill is no longer traditional engineering or management, but the ability to talk to models. Younger builders are becoming fluent in prompting, cross-agent workflows, and systems where AI agents write, review, and coordinate each other, patterns discovered by people actively building, not by institutions.

This reframes what talent and leadership mean. The edge now belongs to those who remain cognitively flexible and let technology reshape how they think and work. In an AI-native world, the most effective founders aren’t the best coders or managers, but the ones who can reason about complex systems and continuously adapt alongside fast-moving tools.

Ultimately, AI becomes a generational filter. Those who grow up fluent in these systems will treat them as a natural extension of thought, while older cohorts experience them as something they must translate through. As with every technological shift, the people who adopt the medium as native are the ones who end up defining the future.

Chapters:

0:00 Intro

01:23 The Intersection of AI and Crypto

06:13 The Role of AI Agents in Software Development

09:00 Shifting Profiles of Founders in Tech

11:55 The Future of Knowledge Work and AI

14:57 Decentralized AI and Security Concerns

17:57 The Future of AI and Crypto Integration

20:51 The Role of Stablecoins in the Crypto Ecosystem

24:01 The Evolution of Legal Systems in Tech

26:46 The Future of Labor and Capital in AI

30:01 Global Perspectives on AI and Crypto

32:54 The Future of Venture Capital in Tech

35:59 The Intergenerational Wealth Transfer of Crypto

39:01 The Future of AI and Crypto Regulation

42:04 The Role of Innovation in Crypto

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