Roseanna Chaldecott spent her life as a high-powered lawyer in Manhattan. But when her best friend and law partner dies suddenly, something snaps. Unsure of her future, Roseanna heads upstate on one tank of gas and with no plans to return. In the foothills of the Adirondacks, Roseanna discovers the perfect hideout in a ramshackle farm. Its seventy-six acres are rich with possibilities and full of surprises, including a mother and daughter squatting on the property. Although company is the last thing Roseanna wants, she reluctantly lets them stay.

New to a small town, Jackie and Paula envision a quiet life for their kids: a young adopted son and two teenage foster children, including the troubled Star. However, they quickly butt heads with their neighbor, Clementine, who disapproves of their lifestyle and is incensed when Star befriends her spirited horse, Comet. Haunted by past tragedy and unable to properly care for Comet, Clem nevertheless resents the bond Star soon shares with the horse.

Russell Ammiano works on the 104th floor of the World Trade Center. On the morning of September 11, 2001, the phone rings while Rusty is rushing to work. The news is devastating: his mother has died of a stroke, leaving his brain-damaged older brother, Ben, alone. This news also saves Rusty's life. He's still at home when two planes hit the World Trade Center--and only one of his friends and colleagues survives.

Ruth and her little brother, Aubrey, are just teenagers when their older brother ships off to Iraq. When Joseph returns, uninjured, only three and a half months later, Ruth is happy he is safe but also deeply worried. How can it be that her courageous big brother has been dishonorably discharged for refusing to go out on duty? Aubrey can't believe that his hero doesn't have very good reasons.

Raymond Jaffe feels like he doesn’t belong. Not with his mother’s new family. Not as a weekend guest with his father and his father’s wife. Not at school, where he’s an outcast. After his best friend moves away, Raymond has only two real connections: to the feral cat he’s tamed and to a blind ninety-two-year-old woman in his building who’s introduced herself with a curious question: Have you seen Luis Velez?

Vida is only 19, but she knows a lot about dying. Her weak heart has kept her on the edge of death her whole life. It hasn't been much of a life. Thanks to her overprotective mother, Vida's only friend is Esther, an elderly Holocaust survivor who lives upstairs. Vida's heart is finally about to give out unless she can get a donor heart in time. Richard is 36 and blissfully married until he gets the call that his beloved wife has died in a car accident. His world falls to pieces.

No longer tolerating her husband’s borderline abuse, Faith escapes to her parents’ California beach house to plan her next move. She never dreamed her new chapter would involve befriending Sarah, a fourteen-year-old on the run from her father and reeling from her mother’s sudden and suspicious death. While Sarah’s grandmother scrambles to get custody, Faith is charged with spiriting the girl away on a journey that will restore her hope: Sarah implores Faith to take her to Falkner’s Midnight Sun, the prized black mare that her father sold out from under her.

Marnie is just 35 when her boyfriend, Brian, drops dead of a sudden heart attack. Stunned by his death, Marnie finds her greatest grief is for Troy, Brian’s son whom she has raised as her own since he was a kindergartener. When he is reclaimed by his train wreck of a birth mother, Troy’s departure drives Marnie to a grief group at the local rec center. There she finds unexpected allies, three strangers who join her in an impulsive road trip from Wisconsin to Las Vegas to reconnect with Troy.

It’s 1965, and life has taken a turn for eighteen-year-old Anton Addison-Rice. Nearly a year after his brother died in a tragic accident, Anton is still wounded - physically and emotionally. Alone for the holidays, he catches a glimpse of his neighbor Edith across the street one evening and realizes that she’s in danger. Anton is determined to help Edith leave her abusive marriage. Frightened and fifteen years Anton’s senior, Edith is slow to trust. But when she needs a safe place to stay, she lets down her guard, and over the course of ten days an unlikely friendship grows.

Former Broadway dancer and current agoraphobic Billy Shine has not set foot outside his apartment in almost a decade. He has glimpsed his neighbors - beautiful manicurist Rayleen, lonely old Ms. Hinman, bigoted and angry Mr. Lafferty, kind-hearted Felipe, and nine-year-old Grace and her former addict mother Eileen. But most of them have never seen Billy. Not until Grace begins to sit outside on the building's front stoop for hours every day, inches from Billy's patio.

Brooke is a divorced single mom, financially strapped, living with her mother, and holding tight to the one thing that matters most: her two-year-old daughter, Etta. Then, in a matter of seconds, Brooke’s life is shattered when she’s carjacked. Helpless and terrified, all Brooke can do is watch as Etta, still strapped in her seat, disappears into the Los Angeles night. Miles away, Etta is found by Molly, a homeless teen who is all too used to darkness. Thrown away by her parents, and with a future as stable as the wooden crate she calls home, Molly survives day to day by her wits.

Trevor’s idea is simple: Do a good deed for three people and ask them to "pay it forward" to three others who need help. He envisions a vast movement of kindness and goodwill spreading beyond his small California town and across the world. However, when Jerry, a bum to whom Trevor gave his allowance, returns to a life of dissolution, the project seems valuable only as a lesson on the dark side of human nature. But ultimately Trevor is vindicated.

On an isolated Texas ranch, Dr. Lucy cares for abandoned animals. The solitude allows her to avoid the people and places that remind her of the past. Not that any of the townsfolk care. In 1959, no one is interested in a woman doctor. Nor are they welcoming Calvin and Justin Bell, a newly arrived African American father and son.

Thirty-year-old Celeste Hamilton's life is at a crossroads: she has just left a disastrous marriage, and her estranged mother has recently died, leaving the family's rose business in jeopardy. Reluctantly, Celeste returns to the family home, a moated manor house in Suffolk, to help her two younger sisters sort out the estate and revive the business.

Grace and Tom Penderford are the luckiest people alive. They have a wonderful marriage, a comfortable life and a beautiful baby girl, Chloe. Then, in a heartbeat, happiness becomes despair, and their lives change forever. When three-year-old Chloe falls ill and dies, Tom and Grace's world is ripped apart. As their family of three becomes two, they must find a way to mend each other's broken hearts...and save their marriage, if they can.