Headmaster Theodore Quinn has lived in Liverpool since coming over from America to fight for Britain in the 1940s. Over ten years later, he is harbouring two secrets and scars that are both physical and emotional. Where women are concerned, he and his secrets are a closed shop, until Tia Bellamy walks into his life. Tia cuts through Theo’s reserve, and the first of his secrets is shared with her.

Now that her family is grown, content in the knowledge that she loves them, Lucy Henshaw decides she is free to leave. She secretly purchases a beautiful house overlooking the Mersey, and there she plans to start afresh. Within hours, she has met some characters: her new neighbour Moira, who is dying, and sees Lucy as the ideal new companion for her husband; Shirley Bishop, cleaner extraordinaire; and Dr David Vincent, who is grieving for the loss of his young son.

Kate Owen is a woman fleeing from the past. Leaving a rewarding job in London, she’s uprooted her life and given away her daughter to keep them both safe. Damaged from a traumatic event that broke her family apart, she attempts to find peace in Liverpool. There she meets the seemingly eligible Alex Price, who offers her a glimpse of a happy future. But there are those in London who can never forget what she did and believe she holds the key to the unfinished business she left behind in the capital.

 1936. Polly's guardian angel has to work overtime when her large family is forced to move from the countryside they love into central Liverpool. Money is desperately short, and with her mother working and her father sick, Polly is easily led astray by the handsome Sunny Andersen. But soon war looms, and Sunny joins the navy to train as a signaller. After the horrors of the May Blitz, Polly, too, decides she wants to help her country and goes into the WRNs. She hears that an old pal, Tad Donoghue from the Dublin slums, is now in the Royal Air Force.

Liverpool, 1940. When war comes to Britain, Jessica Wilson and her friend Ruby seize the opportunity to leave behind the orphanage they grew up in and start new lives in the NAAFI. With only forged papers as identification, the girls expect to be turned away but are delighted with an offer of work. For the first time in their lives they experience real independence, and it isn't long before they're spending their evenings enjoying the delights of Liverpool.

December 1930. With the Depression biting deeper, it looks like many children in the East End will wake up to nothing on Christmas morning. Widower Robbie Graham earns just enough to put food on the table for his children, Ben and Ruthie. Local cake shop owner Flo Hawkins can't bear the thought of any child having nothing for Christmas. Along with her sister, Honour, she hatches a plan to bring some festive cheer to the community.

In 1946, Alice Quigley returns to her childhood home on Penny Lane, having lost her house in Bootle and three sisters to the bombs that fell over Liverpool. Estranged from her husband Dan, she finds comfort in living closer to her remaining sister, Nellie. But even though the bombs have stopped falling, tremors still rock the family when Alice's reviled mother is kicked out of Nellie's home and seeks vengeance.

Liverpool, 1935. Kathy Kelling is coming home to Daisy Street from her first day at the High School, longing to tell her friend, Jane, all about it. The Kellings' life becomes a struggle when Kathy’s brother, Billy, has a serious accident. He needs constant attention, and Mrs Kelling must take in lodgers so that Kathy’s schooling does not suffer. When war breaks out, Kathy and Jane are forced to grow up fast. Kathy meets the handsome Alec Hewitt, but he is more attracted to blonde, bubbly Jane. But Fate has not yet finished with Kathy Kelling.... 

Emmy Dickens lives with her widowed mother in a neat house in neglected Nightingale Court, but Mrs Dickens has always impressed upon her daughter that her main aim in life must be to escape from the court. Emmy sees that marriage is her best way out, and when Peter Wesley, First Officer aboard a cruise ship, asks her to marry him, she is over the moon. Life goes well for the newlyweds; they set up home and start a family. But when Peter is killed and Emmy is left almost penniless, her problems begin.... 

During World War Two, Churchill declared that 'beauty was duty'. But for the women working at the Yardley cosmetics factory in London's East End, it's friendship and family. Nineteen-year-old Lily Gunn runs the conveyor belt in the factory's Lipstick Room with tight reins, though of all the women working there it's her 16-year-old sister who gives her the most trouble. Especially when Rene's new boyfriend Ronnie gets called up to fight, leaving Rene alone and with a big problem.... 

When the Todds move into a flat on the Scotland Road, they are strangers to city life: their previous home was a canal barge. Harry gets a job as warehouse manager and his wife, Martha, works in a grocer’s shop whilst Seraphina trains as a teacher, Angela works in Bunney’s Department Store and young Evie starts at regular school. Then circumstances change, and Seraphina takes a job in Lyon’s Corner House. Customers vie for her favours, including an old friend, Toby.... 

Dympna Byrne lives a simple life with her family on the Connemara coast. She adores her father Micheál, and does her best to help her family by working hard and expecting little. But beneath the surface there are hidden secrets. Dympna’s mother idolises her clever eldest son, yet her attitude to Dympna is puzzling. So when her family find themselves in desperate need of money, it is Dympna who crosses the water to Liverpool to seek a better life. 

When Matthew’s beloved wife Molly died, long before her time, her son Mark grieved as much as anyone. Mark had always been a disappointment to his father – while the family business, a prosperous antiques and junk shop in Manchester, gradually went into decline during Molly’s illness, Mark was more often out stealing than helping out at the store. Tilly Povey, famous for her whiplash tongue and her copious ironing, watched the boy’s decline with a heavy heart from her house across the street.

England, 1943: Home is no longer safe for eight-year-old twins Molly and Jacob. Night after night, wailing bombs and screeching planes skim the rooftops overhead. They cradle each other, shivering in terror, not knowing if they'll live to see dawn. Their mother, Martha, has no choice but to evacuate them to the safety of the countryside. At the train station, Martha bites back tears as she says good-bye to her precious children. Knowing she might never see them again, she gives Jacob a letter, pressing the envelope into his hands and telling him to only read it if they are in danger.

Nell Gunn, Snowball and Esther will be back, along with more characters from Britain's biggest beauty factory, as they battle the twists and turns of war in Stratford. Will Nell find lasting love? Will Snowball reveal what forced him onto the streets? And will Esther be able to tame the wild child she takes under her wing as part of her new bursary? As flowers and vegetables blossom in the Shoot's new Dig for Victory allotment, can the inhabitants really bury their pasts?