Showing titles in Contagious Diseases

In The Black Death: New Lessons from Recent Research, celebrated medievalist Dorsey Armstrong shares the fascinating new story of this old pandemic—revealed by dedicated researchers working with 21st-century technologies and a knowledge of language and history that now provide input from all geographic areas of the medieval world. In seven engaging lectures, Professor Armstrong corrects explanations of the pandemic that are now known to be inaccurate and offers a more robust description of plague biology than has ever been known.

In medical charts, the term "N.A.D." (No Apparent Distress) is used for patients who appear stable. The phrase also aptly describes America's medical system when it comes to treating the underprivileged. Medical students learn on the bodies of the poor - and the poor suffer from their mistakes. Rachel Pearson confronted these harsh realities when she started medical school in Galveston, Texas.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

In mid-January 2020, scientists Ugur Sahin and Özlem Türeci learned of how a new virus that had emerged in Wuhan, China, was spreading. Recognising the threat at once, they dropped everything and committed themselves to developing a vaccine against the disease that would soon be known as COVID-19. No one believed it was possible. But by December, the revolutionary BioNTech-Pfizer mRNA inoculation became the first clinically approved COVID-19 vaccine. Soon it was being injected into the arms of millions, turning the tide on the deadliest pandemic in living memory.

From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.

Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences.

For centuries mankind has waged war against the infections that, left untreated, would have the power to wipe out communities, or even entire populations. Yet for all our advanced scientific knowledge, only one human disease - smallpox - has ever been eradicated globally. In recent years, outbreaks of Ebola and Zika have provided vivid examples of how difficult it is to contain an infection once it strikes and the panic that a rapidly spreading epidemic can ignite.

By investigating thousands of descriptions of epidemics reaching back before the fifth-century-BCE Plague of Athens to the distrust and violence that erupted with Ebola in 2014, Epidemics challenges a dominant hypothesis in the study of epidemics, that invariably across time and space, epidemics provoked hatred, blaming of the "other", and victimizing bearers of epidemic diseases, particularly when diseases were mysterious, without known cures or preventive measures.

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

For the first time in history, the world shut itself down - by choice - all for fear of a virus, COVID-19, that wasn’t well understood. The government, with the support of most Americans, ordered the closure of tens of thousands of small businesses - many never to return. Almost every school and college in the country sent its students home to finish the school year in front of a computer. Churches cancelled worship services. “Social distancing” went from a non-word to a moral obligation overnight.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, William H. McNeill's Plagues and Peoples is a brilliantly conceptualized and challenging achievement (Kirkus Reviews). Upon its original publication, Plagues and Peoples was an immediate critical and popular success, offering a radically new interpretation of world history. With the identification of AIDS in the early 1980s, another chapter was added to this chronicle of events, which William McNeill explores in his introduction to this edition.

Challenging what you know and think about your own body and how it defends you against all sorts of maladies and how it might also eventually be your own downfall, Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body. 

Many sufferers drag themselves from one doctor or alternative practitioner to the next, getting lost in a maze of lab tests, prescription drugs, and treatments. Thousands of dollars and months (or years) later, they realize they are no better off than where they started. Unlocking Lyme puts an end to this desperate quest. Written by Dr. Bill Rawls, a physician who overcame Lyme disease himself, this book is a comprehensive, practical resource full of solutions that work.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

In Vaxxers, we hear directly from Professor Gilbert and her colleague, Dr Catherine Green, as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it. This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm, they separate fact from fiction, they explain how they made a safe vaccine in record time with the eyes of the world watching and they give us hope for the future.

Working in A&E is a challenging job, but nurse Louise Curtis loves it. She was newly qualified as an advanced clinical practitioner, responsible for life or death decisions about the patients she saw, when the unthinkable happened and the country was hit by the Covid-19 pandemic. The stress on the NHS was huge and for the first time in her life, the job was going to take a toll on Louise herself.

The origins of COVID-19 are shrouded in mystery. Scientists and government officials insisted, for a year and a half, that the virus had a natural origin, ridiculing anyone who dared contradict this view. Tech giants swept the internet, censoring and silencing debate in the most extreme fashion. Yet it is undeniable that a secretive facility in Wuhan was immersed in genetically manipulating bat-coronaviruses in perilous experiments. And as soon as the news of an outbreak in Wuhan leaked, the Chinese military took control and gagged all laboratory insiders.

Professor Devi Sridhar has risen to prominence for her vital roles in communicating science to the public and speaking truth to power. In Preventable, she highlights lessons learned from outbreaks past and present in a narrative that traces the COVID-19 pandemic—including her personal experience as a scientist—and sets out a vision for how we can better protect ourselves from the inevitable health crises to come.