Today’s episode features a remarkable leader in the field of gene therapy, Dr. Bobby Gaspar. With over 25 years of experience as a physician and scientist, Bobby has played a pivotal role in redefining treatment options for severe genetic disorders.
As the co-founder and current CEO of Orchard Therapeutics, recently acquired by Kyowa Kirin, Bobby has been at the forefront of advancing gene therapy, particularly in hematopoietic stem cell gene therapy. His groundbreaking work includes some of the earliest studies in patients suffering from severe primary immune deficiencies, propelling these therapies into late-stage clinical trials and bringing hope to countless patients around the world.
Recently recognized on the inaugural TIME100 Health list in 2024, Bobby holds a dual role as a Venture Partner with F-Prime Capital in London, further showcasing his strategic vision in the biotech landscape. His leadership extends beyond Orchard, as he chairs the board of directors at Eligo Biosciences.
An honorary professor of pediatrics and immunology at the University College London, Bobby is dedicated to improving diagnosis and treatment for conditions like metachromatic leukodystrophy through innovative screening and education initiatives.
Join us as we explore Bobby's inspiring journey, his insights into the future of gene therapy, and the ways he is influencing human health on a global scale.

I am thrilled to welcome Steve Paul to Between the Biotech Waves.
With nearly 50 years of experience as a physician-scientist, Steve has made significant contributions to the fields of neuroscience, molecular neuropharmacology, and CNS drug discovery and development. He is the scientific co-founder of Sage Therapeutics, where he played a key role as the interim head of Research and Development during its formative stages which ultimately led to the approval of the first drug for postpartum depression. Additionally, he co-founded Voyager Therapeutics, a pioneering company in CNS gene therapy, and served as its president and CEO.
Steve’s leadership extends to Karuna Pharmaceuticals, where he served as CEO and chairman, developing groundbreaking treatments for schizophrenia and dementia-related psychosis in Alzheimer’s disease. This innovative work culminated in the company’s sale to Bristol-Myers Squibb in 2023 for an impressive $14 billion.
Previously, Steve directed the Appel Alzheimer Disease Research Institute at Weill Cornell Medical College and is currently a professor of psychiatry and neurology at Washington University in St. Louis School of Medicine. His distinguished career also includes 17 years at Eli Lilly, where he held multiple leadership roles, including Executive Vice President for Science and Technology and President of Lilly Research Laboratories. Before his time at Lilly, he spent 18 years at the National Institutes of Health, serving as the scientific director of the National Institute of Mental Health.
Steve's remarkable contributions have earned him numerous prestigious awards, and he has actively participated in many committees and advisory boards throughout his career. He is the author or co-author of over 550 scientific papers and book chapters, solidifying his impact on the field.
Currently, Steve serves as a Venture Partner at Third Rock Ventures and is the recent founder of Seaport Therapeutics.
Join me as we explore Steve’s extraordinary journey and gain insights into the future of neuroscience and drug development.

Today, I are excited to welcome Kent Rogers, the Chief Executive Officer of EveryONE Medicines. Kent brings a wealth of experience to his new role, having held executive leadership positions at renowned pharmaceutical companies as well as emerging biotech firms. With over 30 years of expertise in brand and generic pharmaceuticals, specialty pharmacy, and healthcare supply chain management, Kent has been at the forefront of developing disruptive solutions that enhance access to new medicines targeting critical disease states.
His leadership at EveryONE Medicines focuses on the research, development, and commercialization of individualized precision therapeutics, particularly for children facing rare and ultra-rare diseases. In addition to his role at EveryONE Medicines, Kent is a Venture Partner at ARCH Venture Partners and serves on the board of SlateRx, highlighting his commitment to advancing healthcare initiatives.
Join us as we discuss Kent's extensive career, his vision for EveryONE Medicines, and the innovative strategies he employs to create pathways for access to life-changing therapies. Whether you're a professional in the biotech field or just interested in the future of medicine, this episode promises to be insightful and inspiring.