It is the 32nd millennium, and the Imperium is at peace. The Traitor Legions of Chaos are but a distant memory, and the many alien races that have long plagued mankind are held in check by the Space Marines. When a mission to exterminate one such xenos breed on the world of Ardamantua draws in more of their forces, the Imperial Fists abandon the walls of Terra for the first time in more than a thousand years.

On an Imperial outpost world on the fringes of tau space, the renowned Commissar Ciaphas Cain and his fractious regiment of Valhallan Guard, newly created from the remnants of two devastated units, find themselves in the middle of a war. As the Astra Militarum struggle to contain worldwide civil insurrection, can the wily Commissar Cain identify the real villain before the planet is lost to the Imperium forever?

In the centuries since his return from Commorragh, Fabius Bile has distanced himself from the affairs of friend and foe, content only to oversee the cruel evolution of his New Men. But when his creations are threatened by the monstrous haemonculi of the Thirteen Scars, the Manflayer is forced to seek out new allies and old enemies alike in an effort to preserve all that he has built. Homo Novus must survive...even if Fabius Bile must die to ensure it.   

On the world of Verghast, a grinding war between two hive cities - one loyal to the Imperium, the other fallen to the worship of the Dark Gods - is bolstered by the forces of the Astra Militarum, spearheaded by the Colonel-Commissar Gaunt and the Tanith First and Only. But bitter rivalries and treachery threaten to derail the defence of Vervunhive, and it falls to Gaunt to take command of the Imperial forces and forge victory from an almost certain defeat.   

The shrine world of Divinatus Prime has become lost to the light of the Astronomican, and no ship can piece its veil. Only the Lord of Death himself, Blood Angels Chief Librarian Mephiston, has any hope of discerning the fate of this once pious world. After enacting a powerful blood ritual, Mephiston and an honour guard of his fellow Blood Angels reach the stricken shrine world to find it seized by religious civil war. Each faction fights for dominance of a potent artefact, the Blade Petrific, said to be wrought by the Emperor Himself.  

The war for the fate of mankind blazes on. Though the outer defences have fallen, the walls of the Palace itself remain inviolate as Rogal Dorn, the Praetorian of Terra himself, uses every known stratagem and ploy to keep Horus' vast armies at bay. In Perturabo, the Traitor siegebreaker, Dorn faces an adversary worthy of his skill. A terrible, grinding attrition ensues. The crucial battle for the Lion's Gate spaceport is at the heart of this conflict. With it in their possession, the Traitors can land their most devastating weapons on Terran soil. Dorn knows it must not fall.

The Custodian Guard have stood watch over the Emperor's Palace on Terra since the foundation of the Imperium. Charged with protecting the Master of Mankind from all threats, within and without, their fearsome resolve is renowned throughout the galaxy, and their golden armour is the last thing that a would-be assassin or saboteur will ever see.

Uncompromising and fierce, Commissar Severina Raine has always served the Imperium with the utmost distinction. Attached to the 11th Antari Rifles, she instills order and courage in the face of utter horror. The Chaos cult, the Sighted, have swept throughout the Bale Stars and a shadow has fallen across its benighted worlds. A great campaign led by the vaunted hero Lord-General Militant Alar Serek is underway to free the system from tyranny and enslavement, but the price of victory must be paid in blood.

Constantin Valdor. It is a name that brings forth images of heroism, honour and peerless duty. For it is he who commands the will of the Legio Custodes that most esteemed and dedicated cadre of elite warriors. He is the Emperor’s sword, His shield, His banner and he knows no equal. Clad in shining auramite, his fist clenched around the haft of his Guardian Spear, he is the bulwark against all enemies of the throne, within or without. Nearing the end of the wars of Unity, Valdor’s courage and purpose is put to the test as never before. 

Under almost constant besiegement by the hosts pouring from the Eye of Terror, Cadia acts as a bulwark against tyranny and death. Its fortresses and armies have held back the hordes of Chaos for centuries, but that grim defiance is about to reach its end. As Abaddon's Thirteenth Black Crusade batters Cadia's defences, and armies of the Imperium flock to reinforce this crucial world, a terrible ritual long in the making comes to fruition and the delicate balance of this brutal war shifts.

For 10,000 years, Cadia stood as a bastion against the daemonic tide spewing forth from the Eye of Terror. But now the Fortress World lies in ruins, its armies decimated in the wake of Abaddon the Despoiler and his Thirteenth Black Crusade. Those who survived, though haunted by the loss of their beloved homeworld, remain bloodied and unbarred, fighting ruthlessly in the Emperor’s name. Amongst them is the indomitable Sergeant Minka Lesk.

Sent to avenge the deaths of his brothers and purge a dangerous cult, Imperial Fists Primaris Librarian Aster Lydorran finds a foe beyond imagining on Ghyre. Lydorran must use all his strength, will and psychic might to defeat his hidden enemies and avert catastrophe.

Belisarius Cawl, Archmagos Dominus of the Adeptus Mechanicus, is the most brilliant mind alive. For 10,000 years he has furthered the cause of mankind, working under the aegis of the Emperor and Lord Commander Roboute Guilliman to prevent the inexorable march of the alien and the traitor. Many call him heretic, but all must recognise the magnitude of his achievements, for who else but he was entrusted to create a new generation of Space Marines?  

The hunters have become the hunted. The Night Lords flee to the dark fringes of the Imperium to escape their relentless pursuers - the aeldari of Craftworld Ulthwé. Their flight takes them to the carrion world of Tsagualsa, where their primarch died and their Legion was broken. There, history will repeat itself as a deadly assassin stalks the shadows, and the Night Lords are drawn into a battle they are destined to lose. 

When the world of Armageddon is attacked by orks, the Black Templars Space Marine Chapter are amongst those sent to liberate it. Chaplain Grimaldus and a band of Black Templars are charged with the defence of Hive Helsreach from the xenos invaders in one of the many battle zones. But as the orks' numbers grow and the Space Marines' numbers dwindle, Grimaldus faces a desperate last stand in an Imperial temple.