• Julianna Margulies: That's Life in an ER (Re-Release)
    Jan 19 2026

    This week, we're looking back at Rob's conversation with "The Good Wife" star Julianna Margulies! The two discuss meditating as a family, why she left ER, and Fraterdays! Got a question for Rob? Call our voicemail at (323) 570-4551. Yours could get featured on the show!

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    1 hr and 7 mins
  • Kenny Chesney: Every Rut of Every Highway
    Jan 15 2026

    Singer, writer, and Country Music Hall of Fame member Kenny Chesney joins Rob Lowe to discuss seeing each other in New Orleans, the importance of gratitude, how a failed courtship led him to songwriting, why he decided to write a memoir, life on the road, how “The Boys of Fall” reinvigorated his creativity, and much more. Kenny's memoir, "Heart Life Music," is available now.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    49 mins
  • Nicholas Sparks: Love Stories
    Jan 8 2026

    Rob and "The Notebook" author Nicholas Sparks love to talk writing. One of the best-selling authors of all time, Sparks returns to the show to discuss his new novel, “Remain,” the live musical adaptation of “The Notebook,” the current state of book tours, his collaboration with M. Night Shyamalan, and much more.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    49 mins
  • Julian Edelman: Surrounded by GOATs (Re-Release)
    Jan 5 2026

    This week, we're looking back at Rob's interview with three-time Super Bowl champ Julian Edelman back in March 2023! Hear them discuss Super Bowl LI, Belichick’s strategic silence, how pro football is changing, where they expected Tom Brady to go in 2023, and Julian’s big screen experience on “80 for Brady.”

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    48 mins
  • Michael J. Fox: Exterior Night Jungle Rain (Re-Release)
    Jan 1 2026

    We're throwing it back to Rob's interview with the great Michael J. Fox! The two discuss the balance of realism and optimism, Transcendental Meditation, being in a jungle for six months with Sean Penn, and dissect some of Paul Simon’s most cryptic lyrics. Plus: we learn Michael’s favorite theme song from one of his movies. This episode originally aired in December 2020.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    59 mins
  • Jim Belushi: My Movie Best Friend
    Dec 25 2025

    It’s an “About Last Night” reunion! Rob’s co-star from “About Last Night,” Jim Belushi, joins him to discuss the journey that led to their roles together in the 1986 film, working with Hugh Jackman and Kate Hudson on the new movie “Song Sung Blue,” why he was so impressed by Kristen Stewart, and much more.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    51 mins
  • Natasha Lyonne: Just One More Thing (Re-Release)
    Dec 22 2025

    This week, we're looking back at Rob's conversation with the great Natasha Lyonne! Hear why Natasha feels safe around Maya Rudolph and Amy Poehler, how her love has grown for Detectives Sipowicz and Columbo, and how when you gain fame you need to avoid the dangerous "celebrity vocal sound." This episode originally aired in August 2022.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    49 mins
  • Simon Pegg: It’s Not Called Mission Possible
    Dec 18 2025

    Rob Lowe and Simon Pegg love the films of the 1980s! Actor and filmmaker Simon Pegg joins Rob Lowe to discuss their mutual friend Tom Cruise, the surprise grand slam of "Shaun of the Dead," Rob's old neighbor John Cleese, art in the age of artificial intelligence, and much more.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    51 mins