Evaluating the 90-day safety and technical feasibility of a percutaneous transvenous approach represents a critical milestone for routing cerebrospinal fluid (CSF) – the clear liquid that cushions the brain and spine – directly into the venous system.

In this episode, JNIS Editor, Dr. Michael Chen, talks with corresponding author Professor Adel Malek (Tufts Medical Center, Boston) (1) to discuss his high-impact paper, "Safety of endovascular shunting for normal pressure hydrocephalus from a prospective, multicenter, single-arm study”.

They discuss the results of this 66-patient, prospective trial, exploring how the novel eShunt system accesses the cerebellopontine angle cistern to drain CSF and relieve pressure.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Neurosurgeon Adel Malek, MD, PhD. Chief of the Cerebrovascular and Endovascular Division in the Department of Neurosurgery, Tufts Medical Center; Professor of Neurosurgery, Tufts University School of Medicine, Boston, USA.

The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.

Achieving near-complete reperfusion in medium vessel occlusions (MeVO) is linked to smaller final infarct volumes. However, this did not translate into a statistically significant shift in 90-day functional independence.

In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, and Professor Johanna Ospel (1) discuss the post-hoc analysis of the ESCAPE-MeVO trial, titled "Reperfusion grade and clinical outcome following medium vessel occlusion thrombectomy in the Endovascular Treatment to Improve Outcomes for Medium Vessel Occlusion trial".

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Clinical Associate Professor at the University of Calgary and Senior Lecturer at the University of Basel.

The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.

Headache affects up to 90% of patients following aneurysmal subarachnoid hemorrhage (aSAH), often requiring high-dose opioids that can complicate neurological monitoring.

In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, is joined by Professor Peter Kan¹ to discuss a prospective pilot study investigating a novel dural therapy: the infusion of lidocaine (with or without dexamethasone) via the middle meningeal artery (MMA) during aneurysm embolisation.

They explore the safety of this targeted approach, its impact on Visual Analog Scale (VAS) pain scores, and its potential as an opioid-sparing strategy in the neuro-ICU.

Link to the discussed paper: "Middle meningeal artery infusion for headaches after aneurysmal subarachnoid hemorrhage: a pilot study".

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Texas, USA