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In this episode, Dr. Felice Gersh joins host Dr. Jaclyn Smeaton and DUTCH founder Mark Newman for a deep-dive on progesterone: its physiological roles, concerns around standard-of-care prescribing practices, and more.

Their conversation also explores:

• Progesterone’s role as more than an endometrial protectant
• Supraphysiologic allopregnanolone created by oral micronized progesterone
• The physiological benefits of cyclic dosing versus continuous dosing
• How the gut microbiome impacts progesterone metabolism
• The need for more research on oral micronized progesterone and dosing methods

Show Notes

Learn more about Dr. Gersh’s practice Integrative Medical Group of Irvine and check out her books!

Read Dr. Smeaton’s article on oral micronized progesterone in menopause.

Become a DUTCH Provider to get access to comprehensive patient reports, peer-reviewed and validated research, and expert clinical support.

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In this episode, Dr. Bindiya Gandhi joins host Dr. Jaclyn Smeaton to explore GLP-1 receptor agonists through a whole-person, root-cause lens with a particular focus on women’s health.

Their discussion also covers:

• How GLP-1s work, who benefits most, and how to cease therapy successfully
• The role of leptin resistance in weight struggles
• The risk of muscle loss and bone health during GLP-1 therapy
• Using GLP-1s as part of a comprehensive protocol, including optimizing gut health, strength training, and managing cortisol and sex hormones
• Considerations for menopausal women using hormone therapy in addition to GLP-1s

Show Notes

Learn more about Dr. Bindiya Gandhi and follow her on Instagram @drbindiyamd!

Check out our DUTCH Article on GLP-1s and perimenopause.

Become a DUTCH Provider to get access to peer-reviewed and validated research, comprehensive patient reports, and expert clinical support.

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This conversation between Dr. Sonya Jensen and host Dr. Jaclyn Smeaton covers the science of how stress disrupts female hormone health and the emotions women carry that perpetuate that disruption. They also discuss the physiological mechanisms of chronic stress and how hormone testing can tell patients their stress story.

This episode also highlights:

• How chronic stress and sustained cortisol production can lead to suppressed progesterone
• The downstream effects of resentment and unexpressed emotion
• How a patient’s emotional history connects to their symptoms
• The cortisol/cortisone ratio and what it can tell practitioners and patients about fatigue, low motivation, anxiety, and burnout
• Using the Cortisol Awakening Response on the DUTCH Plus as a clinical conversation tool

Show Notes

Learn more about Dr. Sonya Jensen and follow her on Instagram @drsonyajensen!

Check out Dr. Sonya’s book, Heal Your Hormones, Reclaim Yourself.

Read the ovarian aging study mentioned in this episode.

Become a DUTCH Provider to get access to comprehensive patient reports, peer-reviewed and validated research, and expert clinical support.