Tom McCallister has been in love with his best friend Lyla for as long as he can remember, but what would be the point of telling her that? He's known that it's hopeless ever since she came out to him as a lesbian during their freshman year of college. Lyla likes women, and Tom is definitely not a woman. But when Tom loses both his job and his girlfriend on the same day, Lyla is still the first person he turns to for support. She tells him to drop everything and fly out to see her in New York, confident that some friend time is exactly what he needs to get through his slump.

When Jack’s girlfriend Aimee ends their two-year relationship because he isn’t strong or manly enough for her in her eyes, it’s a devastating blow to his self-esteem. Instead of wallowing in his sadness, he picks himself up and catches a flight to sunny Palm Springs, where he hopes some desert hiking might clear his mind, help him heal, and toughen him up. But Jack gets more than he bargained for from his trip.

Drew Crossfield is a fashion designer with a secret desire that he's never dared to explore, no matter how badly he might want to. When famous style icon naTasha notices him, there's no turning back. She knows a closeted sissy when she sees one, and she’s determined, from the start, to change this drab dresser into the feminized glam girl of his dreams.

Antwon Reynolds is a brilliant scientist working day and night to win fame and fortune by solving the ultimate mystery of mankind - how to understand the mysterious inner workings of women's minds! To further his research, he comes up with a brilliant and daring plan: the creation of a potion which will allow him to transform himself into a woman and conduct first-hand research of the intricacies of the fairer sex. The only barrier to his plan is Duke Owen Montgomery, head of the scientific society, and his biggest critic.

A femboy becomes a girl? A witch offers a potion to a friend to turn him into a woman for a week. If his true inner self ends up relating to the new female body, he’ll stay that way for the rest of his life; if not, he’ll turn back into a male. Will he adapt to a new life with men being interested in him, or will his old paradigms cause him to return to the male form at the end of the week? Will he lose the witch-girlfriend he has always been in love with and end up with a man, or will they come closer together?