It’s November 3, 2020, and Emma McMasters has just been elected the 46th president of the United States. She’s facing a divided Congress and nation, allies that no longer trust America, enemies that have been emboldened, and the legacy of destruction left by the last administration. She must rebuild and reestablish trust in government, in the media, and in the electoral system, all the while carrying the mantle of first female president, and along with it, the hopes and dreams of millions of women and little girls who need her to prove that a woman can get the job done. 

Presidential candidate Jane Kincaid - gorgeous, dynamic and extremely driven - is taking the country by storm, passionately outlining her blueprint for America. Voters quickly fall in love with her...and so, unwittingly, does Secret Service Agent Alexandria Warner. Their mutual attraction begins to take on a fiery life of its own, and soon Jane fears that their intense feelings for each other are a tinder box that could destroy the landscape of her career...and alter the history of the country. 

When orthopedic surgeon Harriet “Harry” Basantes is called to the ER to assess a patient who has been assaulted by her husband, she’s instantly thrust back 16 years to the day her childhood sweetheart, Desi Thompson, walked away and disappeared without a trace. Desi’s always done the right thing, including marrying the man her father insisted was a better match than Harry. But when she ends up in the ER after an argument gone wrong, she can’t help wondering if the right thing is worth the cost.

Thursdays aren't simply another day of the week for Amy Spencer and Ellis Hall. Thursday afternoons sizzle with no-strings sex for the two women, who meet each week in a hotel room to forget their past - and their present. The arrangement works perfectly for Amy, a busy surgeon who's still smarting from a failed relationship. For Ellis, Thursday afternoons act as a pressure valve from her cutthroat job and mistakes in her personal life she's trying to rectify. Soon they discover that their outside worlds are on a collision course with the carefully constructed world they've created.

Nadia Keating has barely started her cardiothoracic fellowship training, but she already has the archetype nailed - she's direct, uncompromising, and suffering from a God complex. Before she can focus on her impressive research, deeply closeted Nadia has a personal project: getting her inconvenient attraction to women out of her system. She picks a stranger online for a one-night stand. Ashley Rylan, the chief of Nadia's department, is her polar opposite - sweet, agreeable, and soft-spoken - and the stranger Nadia unwittingly chooses. 

Avery Weston is doing fine. Sure, she’s not doing as fine as her ex - award-winning actress and current television it girl Elise Hayes - but Avery enjoys her work as a federal air marshal and also enjoys almost being over Elise walking out on their relationship 15 months ago. Then Elise is seated next to her on a flight, and the emotional progress Avery thought she’d made is reset in an instant.

Dr. Jess Riley's life is perfect, ticking all the boxes - successful cardiologist, newborn daughter, and a luxurious condo. That is, until she suddenly collapses from acute heart failure. Her entire world crumples along with her exhausted body. Jess is forced to face facts - she can't keep working endless hours, and she'll have to move back home to recover. To her shock, her mother has already taken in Lena Walker, a struggling artist who isn't a stranger to heartbreak either.

Teddi Baker used to believe in happily ever after. It’s why she became a wedding planner and worked so hard to make her business, "Hopelessly Romantic", successful. But after the catastrophe of her own marriage, Teddi loses her heart, her hope, and half of her assets. She is officially jaded, but she needs every job she can get to make ends meet. When bride-to-be Kelly Scott walks in, Teddi is ready. Until she comes face-to-face with Kelly’s sister: Leah Scott, her ex-wife’s divorce attorney. The one who helped ruin her life.

 Kylie and Regan have been best friends since kindergarten, supporting each other through thick and thin. While everyone thinks they would be perfect for each other, they insist there's no chemistry between them - and Regan should know since she's a chemistry teacher.

Have you ever met someone and felt like you’ve known them in a thousand different lifetimes? Lindsay Hall was a high school senior when she and her friend Patty discovered peach schnapps, listened to a past-life hypnosis CD, and got an up-close look at who she once was. And who she used to love. The knowledge of her past life has always haunted Lindsay.

Morgan Ashworth isn't having a good day. The award for Minion of the Year is slipping out of reach, and she has to administer an afterlife package to one of her human employees. An employee she's attracted to. An employee who'll soon know Morgan isn't quite what she seems. Jane Smith was having a great day. Until her hot boss dropped a bombshell. It's time for Jane to complete the questionnaire to decide where she'll spend her afterlife. 

Caroline Parker knows three things to be true. First, she is going to be Boston's most sought-after divorce attorney by 35. Second, given how terrible her romantic track record is, falling in love isn't in the cards for her. And third, Christmas only brings her bad luck - being broken up with not once, not twice, but three times during the holidays is proof enough of that. When she runs into Hannah Dalton on Christmas Eve, she has no reason to believe her luck will change. After all, though Hannah is probably the most gorgeous woman she's ever seen, she's also straight.

Flirting has never been Denny’s strong suit, but so what if she’s too shy to ask women out? She’s content with her simple life, working as a cashier and helping her sister raise her niece. But then she gets a wrong-number text message from a stranger named Eliza, asking her of all people for dating advice!

Amanda Morgan is a morning show host with a fierce reputation, but a bitter divorce has left her feeling all washed up. Dakota Washington is a young reporter who is flabbergasted to meet her career idol - and biggest celebrity crush - at a friend’s out-of-town wedding. Their night together goes beyond her wildest fantasies. They were never meant to see each other again - until fate steps in, landing Dakota a job at Amanda’s network in New York City. Thanks to a draconian employment contract, the network could fire them on the spot for getting romantically involved.

Sutton Spencer's ideas for her life were fairly simple: finish graduate school and fall in love. It would be a lot simpler if she could pinpoint exactly what she should do when she graduates in less than a year. Oh, and if she could figure out how to talk to a woman without feeling like a total mess, that would be great, too. Charlotte Thompson is very much the opposite.