REVERSE AGING: The Epigenetic Reprogramming Revolution: Yamanaka Factors, Cellular Rejuvenation, Human Trials, and the Race to Turn Back Biological Age cover art

REVERSE AGING: The Epigenetic Reprogramming Revolution: Yamanaka Factors, Cellular Rejuvenation, Human Trials, and the Race to Turn Back Biological Age

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REVERSE AGING: The Epigenetic Reprogramming Revolution: Yamanaka Factors, Cellular Rejuvenation, Human Trials, and the Race to Turn Back Biological Age

By: Hitomi Imai
Narrated by: Rebekah Amber Clark
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What if getting older could be undone?In animals, it already has been. Researchers took cells from old mice, switched them back toward a younger state, and the animals changed too. Blind mice saw again. Aged mice recovered lost memories. Mice treated near the end of life lived more than twice as long. Not slowed. Not delayed with green smoothies and face cream. Undone.For a century, biology textbooks said aging runs one way. Then one quiet laboratory proved them wrong.The man behind it is Shinya Yamanaka. In 2006, using just four proteins, he took an old, fully grown cell and walked it back to the state it had at the start of life. The clock did not slow down. It went in reverse.In June 2026, the waiting ended. A patient in Boston received the first dose of a therapy built on that discovery, the first attempt ever to make a human cell younger.Reverse Aging tells the whole story in plain English. No biology degree needed.Inside, you will learn:What "biological age" means, and why it can differ from the number on your birthday cakeHow the four Yamanaka factors work, in everyday wordsThe mouse studies that restored aging tissueWhy researchers use partial reprogramming, and the cancer risk behind itWho is in the first human trial, and what it will and will not proveThe billion dollar companies racing to be nextWhich anti-aging claims have real evidence, and which are marketing©2026 Hitomi Imai (P)2026 Hitomi Rosner
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