December 1930. With the Depression biting deeper, it looks like many children in the East End will wake up to nothing on Christmas morning. Widower Robbie Graham earns just enough to put food on the table for his children, Ben and Ruthie. Local cake shop owner Flo Hawkins can't bear the thought of any child having nothing for Christmas. Along with her sister, Honour, she hatches a plan to bring some festive cheer to the community.

Laura Cannock is on the run. Suspected of killing her bullying husband, his family are on a merciless prowl for revenge. Fleeing from her beloved home of Bolton to Manchester, Laura seeks refuge with her coal merchant uncle. But it soon becomes clear that a roof over her head comes with a price - of the type so unbearable she must escape once more. Destitute and penniless, a stench-ridden housing court in the back streets of the factories is Laura’s only hope of a dwelling - a place where both the filth and the kindness of neighbours overwhelm.

Seventeen-year-old Constance has had a privileged upbringing in Clapham, with staff to attend to her every need. But her parents have always been cold and distant, never showing her love.Craving affection, Constance falls into the arms of Albie Jones, the cook’s grandson. But one fateful encounter leaves her ashamed and pregnant, and she is soon shunned from the family home. Heartbroken and threatened by scandal, Constance is forced to wed Albie and moves to Battersea, where she suffers unforgiving stares and cruel whispers from the neighbours. 

Bristol, 1939. School leaver Maisie Miles suspects her father, a small-time crook, has an ulterior motive for insisting she gets a job at the W. D. & H. O. Wills tobacco factory but keeps it to herself. She's befriended by effervescent Phyllis Mason and kind-hearted Bridget Milligan who take pity on her and take Maisie under their wing. But beneath their happy-go-lucky exteriors, they all harbour dreams and worries about what the future holds. 

Liverpool, 1940. When war comes to Britain, Jessica Wilson and her friend Ruby seize the opportunity to leave behind the orphanage they grew up in and start new lives in the NAAFI. With only forged papers as identification, the girls expect to be turned away but are delighted with an offer of work. For the first time in their lives they experience real independence, and it isn't long before they're spending their evenings enjoying the delights of Liverpool.

As if everyday life in London's slums wasn't hard enough for Jane Roberts and her three children, the day that ne'er-do-well husband Bert walks out on his family as rent day draws near is a particularly dark time. In the wake of his desertion, the family pulls together to find their way forward, and Jane takes the steps she needs to get a divorce and free them all from Bert in the future. With help from a neighbour who is not all she seems, a lucky break and fresh opportunities, the road ahead starts to look more promising. 

Christmas Eve, 1909. When 11-year-old Lily Larkin is left to fend for herself in an East London workhouse after her dying mother is taken to an infirmary, her future looks bleak. Once she is separated from her twin brother, Davy, her childhood hopes seem to shatter. But Lily's fierce spirit - along with her beloved new friends - help her to endure the miserable drudgery of life at South Grove Workhouse and its cruel supervisor, Miss Fox.

It’s mid-winter, and in the throes of a fierce blizzard, Elsie Redfern and her husband discover an unknown girl in their hay barn about to give birth. After the young mother dies, Elsie takes the infant in and raises her as her own daughter, her precious storm child. Gina grows into a beautiful little girl, but her safe haven turns out to be anything but. Torn away from her home and family, the child finds herself in a nightmare from which there’s no waking, but despite her misery and bewilderment, Gina’s determined to survive.

1850. When Opal Sharp finds herself and her younger siblings suddenly orphaned and destitute, she thinks things can get no worse. But soon three of them - including Opal - are struck down with the illness that took their father from them, and her brother Charlie is forced to make an impossible decision. Unable to afford a doctor, he knows the younger children will not survive. So, unbeknownst to Opal, Charlie takes their younger siblings to the workhouse, where he knows they will at least be fed and have a roof over their heads. Opal is heartbroken and struggles to forgive him. 

At the heart of Dover's Market Square lies the Castle's Café. A bustling, homely place run by the formidable Nellie Castle and her six children. Since the scandalous birth of her beloved son 10 years before, Marianne, Nellie's eldest daughter, has preferred to stay in the kitchen, hidden away from the town gossips. Overcome with shame, Marianne has never revealed the name of Donny's father - not even to her own mother. But with World War II just around the corner, Marianne's past catches up with her. And suddenly the lives of the Castle family become a lot more complicated.

 1936. Polly's guardian angel has to work overtime when her large family is forced to move from the countryside they love into central Liverpool. Money is desperately short, and with her mother working and her father sick, Polly is easily led astray by the handsome Sunny Andersen. But soon war looms, and Sunny joins the navy to train as a signaller. After the horrors of the May Blitz, Polly, too, decides she wants to help her country and goes into the WRNs. She hears that an old pal, Tad Donoghue from the Dublin slums, is now in the Royal Air Force.

Newly married to dashing RAF officer Tom, Irene Farley leaves behind her safe countryside life to move in with his family by the docks in South Shields. Little prepares her for the devastation the Jerry bombers have wreaked on the Sixteen Streets or that they would be living under her mother-in-law's roof, alongside Tom's three brothers and two wives!

Paradise Row, London. December 1865. Snow is falling fast, and Sally Suggs is working tirelessly to bring in enough money to keep bread on the table. Her father, a skilled rag-and-bone man, has fallen ill, and now Sally has taken up his trade. But this is a man’s world and competition is fierce, and Sally’s rival, Finn Kelly, always seems to be one step ahead. 

Lavender Road boasts a pawnbroker, a pub, two rows of terraced working class homes and, at one end, the big house owned by the local brewer. When war breaks out, the lives and fortunes of the families who live in Lavender Road are changed out of all recognition. For Joyce, it means a struggle to keep food on the family table; for Jen it may mean the end of her dream to become an actress; and for Pam, there is the sickening seesaw of emotions as she fights attraction to her handsome lodger and a growing distance from a husband who is judged not fit to enlist.

Two very different girls from this tight-knit community join up as ARP Wardens to do their bit for the home front. Violet Simms lives with her controlling, widowed mother who runs the local pawn shop. At just 20-years-old, Violet longs for friendship, love and escape. It seems her dreams might come true until tragedy strikes on one of the very worst nights of the Birmingham Blitz. Grace Templeton is the eldest in her family of 10 children. Spirited Grace is determined never to become burdened by child bearing and drudgery like her mother.