Scientific evidence has made it abundantly clear that the world's population can no longer continue its present rate of consuming and despoiling the planet's limited natural resources. Scholars, activists, politicians, and citizens worldwide are promoting the idea of sustainability, or systems and practices of living that allow a community to maintain itself indefinitely. Despite increased interest in sustainability, its popularity alone is insufficient to shift our culture and society toward more stable practices. Gary Holthaus argues that sustainability is achievable but is less a set of practices than the result of a healthy worldview. Learning Native Wisdom: Reflections on Subsistence, Sustainability, and Spirituality examines several facets of societies - cultural, economic, agricultural, and political - seeking insights into the ability of some societies to remain vibrant for thousands of years, even in extremely adverse conditions and climates. Holthaus looks to Eskimo and other Native American peoples of Alaska for the practical wisdom behind this way of living. Learning Native Wisdom explains why achieving a sustainable culture is more important than any other challenge we face today. Although there are many measures of a society's progress, Holthaus warns that only a shift away from our current culture of short-term abundance, founded on a belief in infinite economic growth, will represent true advancement. In societies that value the longevity of people, culture, and the environment, subsistence and spirituality soon become closely allied with sustainability.

Ultimately, Holthaus illustrates how spirituality and the concept of subsistence can act as powerful guiding forces on the path to global sustainability. He examines the perceptions of cultures far more successful at long-term survival than our own and describes how we might use their wisdom to overcome the sustainability crisis currently facing humanity.