Showing titles in Genetics

In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. Explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime.

From the author of the acclaimed The Epigenetics Revolution comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of...

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA - but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain - and what might we give up in return? 

The Cancer Club is a collection of very real stories from past and present members of the club–daughters, sons, parents, siblings, friends and the doctors and nurses who stand by your side.

Sociogenomics brings together advances in molecular genetics and traditional social and behavioral science. The key tool is the polygenic index, which allows us to analyze DNA to measure a child's genetic potential. Today, we can estimate a child's adult height, how far they will go in school, and their weight as an adult—all from a cheek swab, finger prick, or vial of saliva. Dalton Conley and other researchers are using this new science to shed light on the ways in which genes shape our world, influencing how each person both creates and responds to the environment around them.

We are on the cusp of a major transformation in healthcare—yet few people know it. At top hospitals and a few innovative health-tech startups, scientists are working closely with patients to dramatically extend their "healthspan"—the number of healthy years before disease sets in. In The Age of Scientific Wellness, two visionary leaders of this revolution in health take us on a thrilling journey to this new frontier of medicine.

In The Genealogical Adam and Eve, S. Joshua Swamidass tests a scientific hypothesis: What if the traditional account is somehow true, with the origins of Adam and Eve taking place alongside evolution? Building on well-established but overlooked science, Swamidass explains how it's possible for Adam and Eve to be rightly identified as the ancestors of everyone. 

Being human entails an astonishingly complex interplay of biology and culture, and while there are important differences between women and men, there is a lot more variation and overlap than we may realize. Sex Is a Spectrum offers a bold new paradigm for understanding the biology of sex, drawing on the latest science to explain why the binary view of the sexes is fundamentally flawed.

A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

An eye-opening investigation into ancestry and origins in the Middle East that synthesizes thousands of years of genetic history in the region to question what it means to be indigenous to any land “Ancestors transcends geography to launch an eye-opening inquiry into the relationship of...

From the former editor of Slate and CEO of Atlas Obscura comes the unbelievable story of “the Nobel Prize sperm bank” and the children it produced—“a superb book about the quest for genius and, ultimately, family” (Malcolm Gladwell, author of The Tipping Point and Talking to Strangers)...

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

What happens when your family tells you one thing, but a DNA test tells you another? Georgina Lawton grew up in a loving family but she didn’t look like anyone else. She has dark eyes, curly hair and brown skin. Both her parents were white. Georgina took a DNA test. The results changed her life forever. With millions around the world using 'do-it-yourself' DNA testing kits, Georgina follows the stories of those learning to live with the results.

Scientists' understanding of life is progressing more rapidly than at any point in human history, from the extraordinary decoding of DNA to the controversial emergence of biotechnology. Featuring pioneering biologists, geneticists, physicists, and science writers, Life explains just how far we've come - and takes a brilliantly educated guess at where we're heading.

The genetic history of the dog is a sensational example of the co-evolution of two species, man and wolf, to each other’s mutual benefit. But how did this ancient partnership begin? To answer this question, Professor Bryan Sykes identifies tantalising clues in the recently mapped genetic...

'Gets right to the heart of what makes us what we are. Read it!' Angela Saini, author of Inferior and Superior: The Return of Race Science Popular science master Brian Clegg’s new book is an entertaining tour through the science of what makes you you. From the atomic level, through life and...

Have you ever wondered what the next century bodes for humanity? Then keep listening... As mankind seeks to guide its own evolution and create intelligent machines, we stand at the brink of doing something no other living being has ever done before. The power to prolong life far beyond natural limits and beat back death itself. The ability to control computers and machines with our minds, and even merge with them. We are poised to become gods.

Noi italiani ci raccontiamo, come altre nazioni moderne, di appartenere a un territorio ben definito, a una cultura coesa, a una storia lineare fatta di antenati che hanno vissuto per millenni nella nostra penisola comportandosi più o meno come continuiamo a fare noi oggi. Le innovazioni tecnologiche degli ultimi vent'anni, per esempio, ci hanno permesso di scoprire che la maggioranza dei nostri antenati neanche era in Italia fino a 5000 anni fa o che le piante e gli animali che ci circondano hanno viaggiato attraverso continenti prima di radicarsi qui.