In 1973, Charlie Safran wrote programs for an MIT group that expected a computer doctor by the year 2000. Fifty years later, the former chief of clinical informatics at Beth Israel Deaconess and past AMIA chair walks Steve Labkoff and Leon Rozenblit through what changed and what didn't: Bayesian decision models for Hodgkin's disease, rules of care in early electronic health records, why those rules were so hard to maintain, and why clinical data will always reflect what gets paid for. His conclusion: reasoning turned out to be the easier part, and technology should make care more human, not less.

Six conversations into Season 2, Steve Labkoff and Leon Rozenblit look back at what they added up to. They revisit Raihan Faroqui on AI agents at the front desk, Greg Raiz on data over gut feel in pre-seed investing, Randi Seigel and Jared Augenstein on the state-by-state map of AI law, Travis Zack on an evidence engine that grades its own sources, Sir Peter Donnelly on genetics as nature's drug trial, and Latha Valluripalli Soorya and Erica Crawford on smart glasses in the autism evaluation. Their read: the field is moving from hype into implementation, efficiency keeps arriving before accuracy, and "AI" may be too broad a word to regulate or even to argue about.

Families who suspect autism can wait up to two years for an evaluation. Dr. Latha Valluripalli Soorya, a clinical psychologist at Rush University Medical Center and co-founder of Argus Cognitive, and Dr. Erica Crawford, Clinical Director at Autism Testing 4 Kids in Dallas–Fort Worth, join Steve Labkoff and Leon Rozenblit to discuss Neurora: smart glasses a clinician wears during a standard autism assessment, with software that measures a child's gaze, facial movement and speech. AT4K was a reimbursed site in its FDA study. They cover what the clinician gets back, the hard cases where the data helps, what the published study does and doesn't show, and why the biggest time savings so far came from report writing.