It is 1942, and after a childhood of suffering in Birmingham, Maryann Bartholomew has built a life of happiness and safety with her husband, Joel, and their children, working the canals on his narrowboat, the Esther Jane. But the backbreaking work and constant childbearing take their toll on Maryann, and the tragic loss of her old friend, Nancy, followed by a further pregnancy lead her to a desperate act which nearly costs her her life.

Emma Brown is a happy-go-lucky child, content to work hard at school, and to play hopscotch with her friends on the pavement outside her house in the run-down Nechells area of Birmingham. As long as everything is all right at home with her Ma and Pa, her little sister Joyce and brother Sid, then life is good. But after Em's mother, Cynthia, has her baby she just doesn't seem to be able to cope.

Three very different women work together at Cadbury's Bournville factory, and their lives become entwined by war and work: and a child called David. Edie, the main character, marries young to escape her unhappy family home. Widowed at 19 and, after losing her child from the marriage, she faces the war grieving and lonely. Then one night during the Blitz, an infant mysteriously abandoned during the bombing is handed into her care.

Evie spent her early years left outside on the step. With a drunk for a father and a neglectful mother, all little Evie has ever craved is a safe home and a normal existence. Her young eyes had seen so much, but this never tainted her spirit. If it wasn't for her best friend, Gary, and a friendly dog called Whisky, Evie might never have made it to her 16th birthday.

For Rose Lucas, a spirited, intelligent girl born into a large family in the slums of pre-war Birmingham, life is hard. But through her friendship with Diana, daughter of a vicar from middle-class Moseley, she learns to aspire to a different and better existence. But life seldom follows dreams, and after losing a love she has fought hard for, and after travelling in Italy, she returns to Birmingham with her hopes shattered. But Rose's powerful spirit will not be defeated.

In the New Year of 1936, Gwen Purdy, aged 21, leaves her home to become a schoolteacher in a poor area of Birmingham. Her parents are horrified, but she has the support of her fiance, a recently ordained clergyman. Her early weeks in Birmingham are an eye-opener: at the school she faces a class of 52 children, some of whose homes are among Birmingham's very poorest.

Sisters Margaret and Annie lost their mother years ago; they long for her every day. Their frightfully protective father keeps the girls close, but he can't protect them forever.... When a scandal rocks the family, the girls are forced to leave their home. The girls flee to Birmingham's jewellery quarter to stay with the one person they can rely on - Uncle Goldsmith. Annie takes up work at a nearby factory, where she learns to forge cutlery, and Margaret is employed as a chain maker.

The early 1900s: Cradley Heath, a town in the Black Country near Birmingham and centre of the world’s chain-making trade. Lucy Butler, a young girl crippled by a cruel accident, lives with her two brothers and widowed mother, a chain-maker barely making ends meet. When tragedy strikes, the Butler family is separated and Lucy is taken in by Bertha Hipkiss, another impoverished chain maker, struggling to look after her own family. 

The Second World War has finally come to a close. Birmingham is welcoming home its menfolk, and a new chapter is beginning in Rachel Booker's life. Her husband has returned, and the family that struggled for survival throughout the uncertain war years is now together. But family life settles into a routine, and Rachel, unsatisfied, starts to yearn for more.

Rachel Booker has a difficult start in life. When her father dies deep in gambling debt, her mother must harden herself to make ends meet but becomes so hard she has little room left for affection or warmth. Mother and daughter work at the open market in Birmingham, selling second-hand clothes or whatever they can find just to put a little food on the table. But the market has a silver lining: it's there that Rachel makes her first childhood friend, Danny.

In 1984, two young mothers meet at a toddler group in Birmingham. As their friendship grows, they share with each other the difficulties and secrets in their lives: Joanne, a sweet, shy girl, is increasingly afraid of her husband. The lively, promising man she married has become hostile and violent and she is too ashamed to tell anyone. When her mother, Margaret is suddenly rushed into hospital, the bewildered family find that there are things about their mother of which they had no idea.

1940: As war closes in and the bombs fall, on the Homefront, two sisters must find their place in a new world of ‘men's' work, in which a telegraph can break your heart and nothing in the future is certain. Growing up in Birmingham, Sylvia and Audrey Whitehouse were always like chalk and cheese. As young women, while Sylvia dreams of her forthcoming life married to fiancé Ian. Audrey can't bear the thought of being tied down by marriage and children.

Two very different girls from this tight-knit community join up as ARP Wardens to do their bit for the home front. Violet Simms lives with her controlling, widowed mother who runs the local pawn shop. At just 20-years-old, Violet longs for friendship, love and escape. It seems her dreams might come true until tragedy strikes on one of the very worst nights of the Birmingham Blitz. Grace Templeton is the eldest in her family of 10 children. Spirited Grace is determined never to become burdened by child bearing and drudgery like her mother. 

Jessica Hart's life is changed forever with the death of her mother. Her manipulative new stepmother tries to force her into marrying an older man, and to Jess, a bright, pretty, young girl who dreams of finding true love, the idea of being trapped in a loveless marriage is unthinkable. So she escapes to Birmingham to her Aunt Olive, the last remaining connection to her mother. But Jess' security is threatened when she meets a friend of the family and falls passionately in love.

Elsie Barker is desperate for a new start after her husband leaves her. When her friend Izzy, herself planning an escape from her abusive boyfriend, tells her about the jobs going for women as narrowboat crew on the canals between London and Coventry, she jumps at the chance. Their new boss, Dorothy, is kind and fair, but it's clear she has a secret of her own. Their crew is completed by Tolly, searching for a new vocation now that her dream job has been snatched away. The work is hard, but the girls forge close friendships that will see them through the darkest times.