London, 1938: Lizzie Larch is a 20-year-old hat maker in London's east end. She is happy and popular, but she carries a secret. Seven years ago she was viciously attacked and recovered in a private sanatorium where she miscarried a child. Lizzie has no memory of the night of the attack, but secrets cannot stay secret for too long. When she starts courting her boss' nephew, a shocking revelation surfaces; threatening to destroy their new-found happiness.

Meet The East End Angels, the newest members of Station Seventy-Five's ambulance crew. Strong-willed Winnie loves being part of the crew at Station Seventy-Five, but her parents are less than happy. She has managed to avoid their pleas to join the WRENS so far, but when a tragedy hits too close to home she finds herself wondering if she's cut out for this life after all. Former housemaid Bella was forced to leave the place she loved when she lost it all, and it's taken her a while to find somewhere else to call home. She's finally starting to build a new life, but when the air raids begin, it seems she may have to start over once again.

Alice Lake has arrived in London from Liverpool to start her training as a District Nurse, but her journey has been far from easy. Her parents think that she should settle down and get married, but she has already had her heart broken once and isn’t about to make the same mistake again. Alice and her best friend, Edith, are based in the East End, but before they’ve even got their smart new uniforms on, war breaks out, and Hitler’s bombs are raining down on London.

The life of a Bomb Girl isn't usually glamourous. But Maggie is getting married, so she is going to make sure her wedding day is - even if she does have to spend every other day slaving on the factory floor. This blasted factory was not what Julia had in mind either. She had always dreamed of attending Oxford University rather than getting her hands dirty, and the easy laughter of the other women intimidates her terribly. But they are all here together in this munitions factory in a Lancashire mill town, sharing firsts, pitching in and getting on. These Bomb Girls are going to do their best at work and in love.

Eliza was left as a small baby at the workhouse in Whitechapel, wrapped in her mother’s shawl, which is all she has of the mother she never knew. At 11 years old, she has survived sickness, near starvation and harsh beatings. Master Simpkins and his cruel daughter rule the workhouse with a rod of iron, but when Romany boy Joe arrives at the workhouse, his spirit and courage give Eliza hope. When she is sold into service, Eliza is relieved to be out of the workhouse and hopes her fortunes are changing for the better, but cruelty and unkindness are everywhere....

Cliffehaven, June 1944. As the planes continue to circle over Cliffehaven, Peggy Reilly’s sister, Doris, must seek refuge after a V-1 blast destroys her home. Rita, Sarah and the other residents at Beach View Boarding House quickly find their peace disturbed, and it’s not long before even Peggy loses her patience. But with more bad news to come, will Doris finally be forced to swallow her pride? Meanwhile Peggy’s father-in-law, Ron Reilly, is delighted when his sweetheart, Rosie, returns home. Until a heartbreaking confession suggests things may never be the same between them. 

Christmas may be the season of goodwill and festive cheer, but not for the poor of 1950s Liverpool. And for St Angelus Hospital in Lovely Lane, it is frantically busy. There are the old, the dying, the children and the emergencies.

The nurses, known locally as the Angels of Lovely Lane, are run off their feet. Dana, Beth, Pammy and Victoria hardly have time to catch their breath, let alone have a Christmas of their own.

Her strength is all she has left.... When Dorothy meets Robbie, she falls for him quickly, and it’s not long before the pair are engaged. But then an unexpected pregnancy puts everything at risk, and Dorothy is left alone - with Robbie nowhere to be seen. Heartbroken, Dorothy picks up the pieces of her life as a working girl in Battersea, helping to support her mother and father. But before long, things start to become difficult. Her father’s health is worsening, money is tight and, worst of all, Robbie hasn’t come back for her. 

Summer, 1936. Newly trained midwife Hazel Price returns to the Yorkshire streets of her childhood, only to find that her modern methods and 'stuck-up' ways bring her into conflict with her family and other formidable residents of Raglan Road. Determined, Hazel battles on, assisting with home deliveries and supporting the local GP. The days are long and hard, but Hazel brings knowledge and compassion to the work she loves.

It's 1939, and the Brogan family of London's East End are ready to show Hitler what for. But things don't seem so rosy when rationing, evacuation and air raids start to put this larger-than-life family to the test. When a mysterious young man arrives at the Brogans' local parish church, he provides just the dazzling distraction they need - and, for eldest daughter Mattie, the promise of more than she'd ever wished for. But as the pair fall deeper in love, they are drawn into secret dangers, rife on the very London streets they call home.

Sisters Carol and Jackie haven't had the easiest of childhoods, but as they grow up and begin their own lives, both hope for happier times ahead. Stylish Carol works in Lewis' department store while Jackie dreams of a career on the stage. But the sisters are heartbroken when they discover they have been dating the same man, and an unexpected pregnancy causes a rift between them. As the sisters' troubles spiral, will their sisterly bond be destroyed forever?

Wood Green, North London, November 1913. The storm clouds of war gather overhead while one brave girl fights to save her family.... After her mother dies, Livvie Bone knows it's down to her to protect her younger siblings from their drunken father. But life on the worst street in London is dark and dangerous, and one night she needs protection herself. When the mysterious Joe Hunter steps in to help her, Livvie's fascinated by him, in spite of his unsavoury reputation.

Cliffehaven, May 1944. The tension is rising for Peggy Reilly and the inhabitants of Cliffehaven as the planes continue to roar above the town, and there is still no news of the long-awaited Allied invasion into France. There seems to be no end in sight of this war, which has scattered her family and brought conflict right to the door of Beach View Boarding House, but Peggy cannot work miracles, and the toll of the war is beginning to weigh on her slender shoulders.

When her beloved father is killed in the Blitz, trainee nurse April Harvey is all alone in the world. Desperate to find the family she craves, she heads to Truro, her mother's hometown. But danger and heartbreak lurk even in Cornwall, and when the American GIs arrive, April finds her life turned upside down as she discovers that some people are not to be trusted. Especially when it comes to her budding romance with Major Crawford Dunbar. As vicious rumours emerge, April fears there will never be a future for them. 

The festive season is approaching, and the Bomb Girls are determined to make this a year to remember. With Myrtle's health in decline, Edna's love life beginning to take flight and a shy new arrival in their midst, life is never quiet in Pendle. But Gladys, back from performing for the troops, is sullen and sad, and her friends are sure she is hiding something.